Results 181 to 190 of about 1,919,659 (338)

POLE Deficiency Exacerbates Diesel Engine Exhaust‐Induced Genomic Instability and Malignant Transformation of Bronchial Epithelial Cells

Advanced Science, EarlyView.
This study establishes a diesel engine exhaust (DEE)‐induced malignant transformation model in bronchial epithelial cells. Whole genome sequencing（WGS） and RNA‐seq reveal DEE‐induced mutational signatures and gene expression profiles. Mechanistically, DEEaffect polymerase epsilon (POLE) and mismatch repair, driving genomic instability and promoting ...
Pimei Zhang, Zhaoxu Wu, Qiang Ju, Nuo Xu, Xian Chen, Hongguang Chen, Shuaishuai Yang, Jing Ji, Yanjie Zhao   +8 more
wiley   +1 more source

Job Accommodations and Job Loss From Unilateral Vocal Fold Paralysis. [PDF]

Otolaryngol Head Neck Surg
Lakpa KL, Bowen A, Menon E, Ring S, Nordby P, Rasmussen M, Arroyo N, Zhao J, Fernandes-Taylor S, Francis DO, CoPE Collaborative.   +10 more
europepmc   +1 more source

The DEC2‐SCN2A Axis is Essential for the Anticonvulsant Effects of Cannabidiol by Modulating Neuronal Plasticity

Advanced Science, EarlyView.
This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song, Yifan Wang, Lili Wang, Chang Guo, Shiqi Liu, Yi Rong, Jiawen Tian, Chao Peng, Yuying Shao, Zhixiong Ma, Na Li, Jingliang Zhang, Zijun Peng, Xu Yan, Hangwei Fa, Xinyue Ma, Jie Dong, Jinping Ji, Chen Yang, Haocheng Chen, Jing Liang, Qi Sun, Yang Yang, Weining Ma, Zhuo Huang   +24 more
wiley   +1 more source

Epidemiology: a partnership of technical expertise and clinical insight. [PDF]

BMJ Med
Burgess S, Lawlor DA.
europepmc   +1 more source

The modern aspects and actual problems of the service of emergency in medicine of the republic of Karakalpakstan on prehospital stage under reforms of Uzbekistan public health system

Сеченовский вестник, 2014
In the given article explored and viewed modern condition and problems of the service of emergency medicine of the Republic Karakalpakstan at organizations and rendering emergency medical help to population on system stage of the public health of Uzbekistan.
openaire   +1 more source

Workshop on manpower development and training in toxicology and chemical safety. Luxembourg, 28 November - 2 December 1983. Industrial health and safety. EUR 9619 EN [PDF]

, 1984
Berlin, A., Smith, E., Tarkowski, S.
core  

Alistipes senegalensis is Critically Involved in Gut Barrier Repair Mediated by Panax Ginseng Neutral Polysaccharides in Aged Mice

Advanced Science, EarlyView.
An integral functional axis through which GPN and functional metabolites of Alistipes senegalensis can hydrolyze tryptophan into indoles. Furthermore, the Alistipes senegalensis‐indole‐AhR pathway is found to be associated with increased expression of tight junction‐associated proteins and activation of gut stem cells.
Dandan Wang, Hui Wang, Yingna Li, Jing Lu, Xiaolei Tang, Dan Yang, Manying Wang, Daqing Zhao, Fangbing Liu, Shuai Zhang, Liwei Sun   +10 more
wiley   +1 more source

Correction: Measuring digital health literacy and its associations with determinants and health outcomes in 13 countries. [PDF]

Front Public Health
Levin-Zamir D, Van den Broucke S, Bíró É, Bøggild H, Bruton L, De Gani SM, Søberg Finbråten H, Gibney S, Griebler R, Griese L, Guttersrud Ø, Klocháňová Z, Kucera Z, Le C, Link T, Mancini J, Miksova D, Schaeffer D, Ribeiro da Silva C, Sørensen K, Straßmayr C, Telo de Arriaga M, Vrdelja M, Pelikan J.   +23 more
europepmc   +1 more source

Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia

Advanced Science, EarlyView.
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji, Yongli Ye, Jiadi Sun, Lina Sheng, Jinyou Li, Jin Yang, Bing Wu, Yuting Wang, Xingxing Gao, Liang Luo, Jianfeng Ping, Yinzhi Zhang, Xiulan Sun   +12 more
wiley   +1 more source

Identifying the components of prehospital emergency preparedness in radiological and nuclear incidents: a scoping review. [PDF]

BMC Emerg Med
Yadollahifar S, Aminizadeh M, Nasiriani K, Tafti AAD, Sefidkar R, Mirzaei S.   +5 more
europepmc   +1 more source