Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
UA Little Rock Seminar in Public History (HIST 7391) files on the Little Rock Port Authority, 2017 [PDF]
This collection contains the project report, interviews, and transcripts from the University of Arkansas at Little Rock's Seminar in Public History's 2016 project,; Project staff: Jared Craig, Randall Crawford, Michael Fondren, Lyle Grisham, Neal ...
University of Arkansas at Little Rock. Department of History.
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Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
ENTERIC PROTOZOAN PARASITES IN STRAY CATS IN KUWAIT WITH SPECIAL REFERENCES TO TOXOPLASMOSIS AND RISK FACTORS AFFECTING ITS OCCURRENCE [PDF]
In Kuwait, stray cats were surveyed for enteric protozoan infection using fecal examination and their sera were tested for Toxoplasma gondii IgG using indirect hemagglutination test (IHAT) as well as for feline immunodeficiency virus (FIV)antibodies and ...
QAIS MAJEED +4 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
THIRD ANNUAL REPORT OF The Board of Directors TO The Advisory Board OF SOUTH CAROLINA PUBLIC SERVICE AUTHORITY [PDF]
The South Carolina Public Service Authority makes annual reports to the Advisory Board, which reports shall be submitted to the General Assembly by the Governor, in which full information as to all of the Acts of said Board of Directors shall be given ...
South Carolina Public Service Authority
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Background The COVID-19 pandemic, declared in March 2020, caused significant morbidity and mortality globally. This study aims to estimate the costs associated with managing COVID-19 infected patients in Regina. Method The study focuses on the direct and
Olanrewaju Medu +10 more
doaj +1 more source
INDEPENDENCE OF PUBLIC PROCUREMENT AUTHORITY [PDF]
Nowadays, many countries suffer from loss of confidence of their citizens. Huge protests are spread throughout many states even in the EU. The time has come to analyse the principles of good governance in order to make states trustworthy organisations again.
openaire +1 more source
Public authority liability and the cost of disasters [PDF]
We examine the influence of introducing public authority liability in the context of disasters. In an ideal setting a rule of comparative negligence would incentivise the government to take an optimal amount of care. The citizen, being the residual bearer of the loss, would consequently also take optimal care.
DE MOT, Jef, Faure, Michael G.
openaire +3 more sources

