Results 61 to 70 of about 362,645 (316)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Royal Religious Authority: Morocco’s "Commander of the Faithful" [PDF]

, 2019
King Mohammed VI of Morocco has cultivated the country’s image as a bastion of moderate Islam and of himself as a strategic partner, but to what extent does his international reputation correspond to public opinion in Morocco?
Sheline, Annelle R.
core  

Selective extraction of thiophene from n-alkanes using methylimidazolium [NTf2] ionic liquids: Experimental LLE and NRTL modeling

Chemical Thermodynamics and Thermal Analysis
The removal of sulfur containing compounds, particularly aromatic species like thiophene from transportation fuels remains a major challenge despite the current industrial desulfurization methods.
Husain Bahzad, Abubaker Mohammad, Abdullah Aljasmi, Khaled Alkhaldi, Adel Al-Jimaz, Mohammad AlTuwaim   +5 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

SIXTH ANNUAL REPORT OF The Board of Directors TO The Advisory Board OF SOUTH CAROLINA PUBLIC SERVICE AUTHORITY JULY 1, 1940-·JUNE 30, 1941 [PDF]

, 1941
The South Carolina Public Service Authority makes annual reports to the Advisory Board, which reports shall be submitted to the General Assembly by the Governor, in which full information as to all of the Acts of said Board of Directors shall be given ...
South Carolina Public Service Authority
core  

State of South Carolina Public Employee Benefit Authority Basic Long-Term Disability Income Plan GASB Statement No. 75 Accounting and Financial Reporting for Postemployment Benefits Other Than Pensions as of June 30, 2023 [PDF]

, 2023
This report provides information on behalf of the State of South Carolina Public Employee Benefit Authority (PEBA) in connection with the Governmental Accounting Standards Board (GASB) Statement No.
South Carolina Public Employee Benefit Authority
core  

From Knowledge to Action: Enhancing Herpes Zoster Vaccine Uptake in Diabetic Patients Through Targeted Interventions

Vaccines
Background/Objectives: Vaccinations are a cost-effective strategy to reduce morbidity and mortality from infectious diseases, particularly in individuals with diabetes mellitus (DM).
Marco Fabbri, Giorgio Cavalli, Valeria Frassineti, Paolo Di Bartolo, Chiara Reali, Elizabeth Bakken, Michela Morri, Gianluigi Belloli, Gianpiero Mancini, Manuela Chiavarini, Giulia Silvestrini   +10 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

GASTROINTESTINAL PARASITES AMONG HORSES IN KUWAIT [PDF]

Journal of the Egyptian Society of Parasitology
This study determined the gastrointestinal parasites prevalence among horse breeds in Kuwaitover the year 2025. Morning fecal samples from 230 from Arabian and non-Arabian horses acrossfive localities were collected and examined using sodium chloride ...
Adawia Henedi, AHMED AL-HAMAD, ABDULRAHMAN AL-SHAMMARI   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source