Results 51 to 60 of about 1,624,413 (300)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Belief Heterogeneity and the Restart Effect in a Public Goods Game

Games, 2018
We explore how subjects with heterogeneous beliefs respond to a surprise restart in a linear public goods game played for 20 rounds using either a “partners„ or a “strangers„ protocol. There are two restarts: one prior to Round 11
Ananish Chaudhuri
doaj   +1 more source

Religious identity and perceptions of afterlife gleaned from a funerary monument to a young girl from (late) Roman Melite [PDF]

, 2017
Possibly late during the Roman occupation of Malta, a young deceased girl had a funerary monument set up in her memory by her loving mother. Analysis of both epigraphic content and iconographic elements on this monument would show that the mother; at ...
Azzopardi, George
core  

Public Belief in the “Great Replacement Theory”

International Migration Review
The “Great Replacement Theory” (GRT) is an extremist narrative that has gained increased prominence within anti-immigration and conspiratorial discourses in Western societies, yet remains understudied. We first conceptualize the GRT as a narrative that typically claims that white majorities are being deliberately replaced by non-white immigrants in a ...
James Dennison, Alexander Kustov
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Betting and Belief: Prediction Markets and Attribution of Climate Change

, 2016
Despite much scientific evidence, a large fraction of the American public doubts that greenhouse gases are causing global warming. We present a simulation model as a computational test-bed for climate prediction markets. Traders adapt their beliefs about
Gilligan, Jonathan M., Nay, John J., Van der Linden, Martin   +2 more
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

The Importance of Country of Origin in Vaccine Messaging for H-2A Farmworkers

Journal of the Georgia Public Health Association
Background: H-2A farmworkers are disproportionately vulnerable to COVID-19 and understanding their beliefs regarding COVID-19 vaccines is important for public health outreach, yet to date little research has examined the influence of country of origin ...
The Importance of Country of Origin in Vaccine Messaging for H-2A Farmworkers
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Open-mindedness predicts support for public health measures and disbelief in conspiracy theories during the COVID-19 pandemic across 68 countries

Judgment and Decision Making
The COVID-19 pandemic has illustrated the importance of public support for non-pharmaceutical public health interventions and the perils of rampant spread of misinformed and conspiratorial beliefs.
Philip Pärnamets, Mark Alfano, Robert M. Ross, Jay J. Van Bavel   +3 more
doaj   +1 more source