Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Pridobitev lastninske pravice nad nepremičninami v javno korist : Acquisition of Real Property for Public Benefit [PDF]
SI: Pridobitev lastninske pravice nad nepremičninami je moč družbene skupnosti, da pridobi nepremičnino, tudi brez soglasja njenega lastnika ali uporabnika, za namen javne koristi.
Miran Ferlan +3 more
doaj
Devletinvatandaşlar üzerindeki üstün gücünün ön planda olduğu alanlardan biri dekamulaştırma işlemidir. Kamulaştırma sürecinde bireysel fayda ile kamusal faydaçatışabilmekte ve kamulaştırmaların meşruiyeti çoğu zaman vatandaşlarcasorgulanabilmektedir ...
Ali Rıza Sandalcılar +4 more
doaj +1 more source
Estimating the Under-ascertainment of COVID-19 cases in Toronto, Ontario, March to May 2020
Background: Public health surveillance data do not always capture all cases, due in part to test availability and health care seeking behaviour. Our study aimed to estimate under-ascertainment multipliers for each step in the reporting chain for COVID-19
Binyam N Desta +6 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
GENDER AND PUBLIC SPENDING ON EDUCATION IN PAKISTAN: A CASE STUDY OF DISAGGREGATED BENEFIT INCIDENCE [PDF]
To what extent has government education spending in Pakistan been effective in reducing gender gaps in enrollments? To answer this question, this article reviews the benefit incidence of government education spending.
Muhammad Sabir
core +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Marginal Benefit Incidence Analysis of Public Spending in Nigeria [PDF]
This study estimates the progressivity of benefit, the average benefit incidence and the marginal benefit incidence of public spending on selected public services in Nigeria, using data from the Nigeria Bureau of Statistics (NBS) 2004 Living Standard ...
Reuben Adeolu Alabi +4 more
core
الرقابة القضائية المستحدثة على السلطة التقديرية للإدارة في قرارات نزع الملكية العامة من خلال نظرية الموازنة بين المنافع والمضار (دراسة تطبيقية مقارنة) [PDF]
كان أول إعمال لنظرية الموازنة بين المنافع والمضار في القضاء الإداري الفرنسي في مجال الرقابة القضائية على سلطة الإدارة التقديرية وذلك في ظل القضايا ذات الطابع الاقتصادي بشكل عام، وعلى وجه التخصيص في القضايا المتعلقة بنزع الملكية للمنفعة العامة، إذ يقوم ...
محمد ناصر راشد محمد الطنيجي و د/ سام سليمان دله
doaj +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source

