Results 61 to 70 of about 14,528,667 (243)
BMC Public Health, 2017 Background Increasing prevalence of childhood obesity and its related consequences emphasises the importance of developing and evaluating interventions aimed at prevention.
T. L. Griffin +5 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Building and Managing Facilities for Public Services [PDF]
We model public-private partnerships in building and managing facilities for the provision of public services. In particular, we analyze both the desirability of bundling the building and management operations, and the optimal allocation of ownership ...
Bennett, John, Elisabetta Iossa
core
Body image dissatisfaction in patients with inflammatory bowel disease: a systematic review protocol
Systematic Reviews, 2018 Background Inflammatory bowel disease (IBD) is a debilitating chronic disease characterised by inflammation and ulceration of the gastrointestinal tract. It is associated with a range of debilitating symptoms and reduced quality of life.
Sophie Elizabeth Beese +3 more
doaj +1 more source
Analysis of the Technical Condition of a Late 19th Century Public Building in Łódź. [PDF]
Materials (Basel), 2023 Grzmil W, Zapała-Sławeta J, Juruś J.
europepmc +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Tiffin-Seneca Public Library 1970s Need For New Building
, 1970 Photographs and typed explanations gathered into a 3-ring binder regarding the need for a new and larger building for the Tiffin-Seneca Public Library in the 1960s/1970s.
Tiffin-Seneca Public Library
core
Prevalence of Legionella in a Public Building Water Plumbing System During COVID-19 Lockdown. [PDF]
Environ Health (Wash), 2023 Li X, Xu J, Wu J, Weir MH, Xi C.
europepmc +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Impacts of Architectural Sights on Anxiety Relief in a High-Density City
Engineering ProceedingsDue to rapid urbanization, high-density cities have become a dominant human habitat, and sustainable urban development has become a key concept in urban governance.
Yung-Chia Chiu +3 more
doaj +1 more source