Results 81 to 90 of about 2,254,914 (312)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

EFFICIENCY AND CORE PROPERTIES OF VALUATION EQUILIBRIUM WITH INCREASING RETURNS [PDF]

open access: yes
This paper considers market economies involving the choice of a public environment when there are nonconvexities in production. It discusses the decentralization of efficient allocations by means of valuation equilibrium, adapting to many private goods ...
Antonio Villar Notario, Peter Hammond
core  

Toward the Integration of Economics and Outdoor Recreation Management [PDF]

open access: yes, 1986
The general theme of this bulletin is that improved management of public-sector recreational resources is a multidisciplinary task. To this end, we attempt to integrate elements of outdoor recreation management theory and economics.
Jubenville, Alan   +2 more
core  

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Determinants of corporatization in Togo: capital, credit, and sectoral disparities

open access: yesTheory and Practice of Public Administration
This article explores the determinants of corporatization in Togo, focusing on access to credit, capital, and the domain of operation. Corporatization aims to enhance efficiency, transparency, and financial performance of public enterprises by aligning ...
Kokouvi Kunalè Mawuena   +2 more
doaj   +1 more source

Public Value under Chaotic Conditions

open access: yesEesti Majanduspoliitilised Väitlused, 2018
Economic interpretation of public value was elaborated in welfare theory and public choice literature. Nowadays public value describes the value that an organization contributes to society (Moore 1995).
Peter Friedrich, Diana Eerma
doaj   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

The Role of Public Choice Theory in International Relations and European Studies

open access: yesCzech Journal of International Relations, 2006
While Marek Loužek has drawn attention to several issues important for International Relations (IR), his conclusions are highly controversial. In his identification of the basic theoretical approaches to international relations, Loužek disregards ...
Jan Karlas
doaj  

Mechanism Choice [PDF]

open access: yes, 2009
This chapter reviews the literature on the selection of regulatory policy instruments, from both normative and positive perspectives. It first reviews the mechanism design literature to identify normative objectives in selecting among the menu or toolbox
Richman, Barak D., Wiener, Jonathan B.
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

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