Results 81 to 90 of about 17,702,281 (301)

Public Choice: an Overview [PDF]

open access: yes
Public Choice begins with the observation that in politics, as in economics, individuals and institutions compete for scarce resources and that, therefore, the same methods of analyses used by economists to explain the behaviour of consumers and ...
Borooah, Vani
core  

Rational Choice and EU Politics [PDF]

open access: yes, 2007
[From the introduction]. Rational choice approaches to politics did not originate in the study of the European Union (EU), nor is ‘rational choice’ as such a theory of European integration or of EU politics.1 Rational choice, like constructivism, should ...
Pollack, Mark A.
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Desperately seeking streaming: CHOICE digital consumers paying for content behaviour and attitudes

open access: yes, 2015
Has the launch of new streaming services in Australia had an impact on the ways Australians access digital content or is a punitive regulatory approach necessary to reduce piracy?
Choice
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

NARAL Anti-Choice Scare Tactic Flyer

open access: yes, 2017
Flyer denouncing anti-choice scare ...
NARAL Pro-Choice America
core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Public Choice and the Economic Analysis of Anarchy: A Survey [PDF]

open access: yes
Public choice economists began studying the economics of anarchy in the 1970s. Since then, the amount of research on anarchy has burgeoned. This article surveys the important public choice contributions to the economics of anarchy.
Stringham, Edward P., Powell, Benjamin
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Remarks on network public theory

open access: yesManagerial Economics, 2014
This paper is a trial of capturing of a relation between traditional public sphere atrophy and the augmentation of a network public sphere. A thesis is advanced that the traditional public sphere is subject of the atrophy, however, the entire network ...
Marcin Brol, Sławomir Czetwertyński
doaj   +1 more source

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