Results 141 to 150 of about 570,744 (306)

GloPath: An Entity‐Centric Foundation Model for Glomerular Lesion Assessment and Clinicopathological Insights

open access: yesAdvanced Science, EarlyView.
An entity‐centric foundation model, GloPath, is introduced for comprehensive glomerular lesion assessment from routine renal biopsy images. Trained on over one million glomeruli, the framework enables robust lesion recognition, grading, and cross modality diag nosis, while uncovering large‐scale clinicopathological associations.
Qiming He   +28 more
wiley   +1 more source

TWIN DEFICITS AND ROMANIA’S MACROECONOMIC VULNERABILITY: AN ASSESSMENT IN THE CONTEXT OF CURRENT ECONOMIC CHALLENGES [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie
Twin deficits — the budget deficit and the current account deficit — represent important factors in assessing Romania’s macroeconomic stability, particularly in the volatile context of the global economy. The evolution of these deficits reflects both
GOIA IZABELA DIANA
doaj  

Restoring Iron Homeostasis via Smoothened Inhibition: A Novel Strategy Against Hearing Loss

open access: yesAdvanced Science, EarlyView.
 . ABSTRACT Sensorineural hearing loss (SNHL) induced by noise or aminoglycoside antibiotics is a significant public health concern without any FDA‐approved pharmaceutical therapies. Dysregulation of iron homeostasis and its subsequently induced ferroptosis has increasingly been identified as a key mechanism underlying cochlear hair cell (HC) damage ...
Huanyu Mao   +9 more
wiley   +1 more source

Economic policy dilemmas in front of the crisis

open access: yesPSL Quarterly Review, 2010
The article is an introduction to the new issue of the Journal. It provides an overview of the current economic and financial situation and summarises the main topics dealt with by the following articles.
Alessandro Roncaglia
doaj  

Cis‐ and Trans‐Regulatory Factors Independently Shape Phenotypic Heterogeneity of Retinitis Pigmentosa

open access: yesAdvanced Science, EarlyView.
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui   +9 more
wiley   +1 more source

Hit list? [PDF]

open access: yes
Budget ; Expenditures, Public ; Budget ...
William Burke
core  

Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions

open access: yesAdvanced Science, EarlyView.
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang   +4 more
wiley   +1 more source

The national debt: a secular perspective [PDF]

open access: yes
An examination of the various factors that have determined the level and growth of the federal debt over the past 40 years, with some perspective on future levels of federal debt.Debts, Public ; Budget ...
E. J. Stevens, John B. Carlson
core  

Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China

open access: yesAdvanced Science, EarlyView.
This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang   +3 more
wiley   +1 more source

Economic costs of large public sector deficits and high inflation: The Argentine lesson [PDF]

open access: yes
The objective of this paper is to analyse the Argentine experience of large public sector deficits and high inflation, to elaborate the collection and dynamics of the inflation tax used to public financing and to identify the economic costs of this ...
Fischer, Bernhard, Trapp, Peter
core  

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