Results 141 to 150 of about 11,755,698 (310)

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen   +5 more
wiley   +1 more source

Institutional Arrangements and Fiscal Performance: The Latin American Experience [PDF]

open access: yes
This paper considers whether institutional factors, in this instance electoral systems and procedures, affect Latin American countries` fiscal performance as measured by the size of the public sector, fiscal deficits, the size of the public debt, and the
Ernesto Talvi   +2 more
core  

TWIN DEFICITS AND ROMANIA’S MACROECONOMIC VULNERABILITY: AN ASSESSMENT IN THE CONTEXT OF CURRENT ECONOMIC CHALLENGES [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie
Twin deficits — the budget deficit and the current account deficit — represent important factors in assessing Romania’s macroeconomic stability, particularly in the volatile context of the global economy. The evolution of these deficits reflects both
GOIA IZABELA DIANA
doaj  

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

open access: yesAdvanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song   +5 more
wiley   +1 more source

Twin deficits in Cambodia: Are there Reasons for Concern? An Empirical Study [PDF]

open access: yes
This study examines the inter-linkages between Government budget balance, and external balance for a transition economy in South East Asia – Cambodia.
Tuck Cheong Tang, Evan Lau
core  

Government Deficit, Public Investment and Public Capital in the Transition to an Aging Japan [PDF]

open access: yes, 2002
Technical ReportThis paper tires to examine the effects of government deficits, public investment, public capital and public pension policies on the tax burden, capital accumulation and economic welfare in the transition to an aging Japan by applying a ...
Kato, Ryuta Ray
core  

Economic policy dilemmas in front of the crisis

open access: yesPSL Quarterly Review, 2010
The article is an introduction to the new issue of the Journal. It provides an overview of the current economic and financial situation and summarises the main topics dealt with by the following articles.
Alessandro Roncaglia
doaj  

A Dual‐Modal Wearable PPG Smartwatch with AI‐Enhanced Correction for High‐Accuracy and Continuous AF Burden Assessment

open access: yesAdvanced Science, EarlyView.
ABSTRACT Atrial fibrillation (AF) increases the risk of stroke and heart failure, yet accurate quantification of AF burden in daily life remains difficult. Although smartwatch photoplethysmography (PPG) supports continuous monitoring, complex rhythms and signal noise can impair burden estimation.
Song Zuo   +27 more
wiley   +1 more source

Inflation divergence and public deficits in a monetary union [PDF]

open access: yes
We reconsider the link between domestic public debts and average and domestic inflation rates in a monetary union, using a modified version of a model by Beetsma and Vermeylen (2002).
Jerome Creel, Jacques Le Cacheux
core  

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

open access: yesAdvanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li   +8 more
wiley   +1 more source

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