Results 41 to 50 of about 15,629,087 (290)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Across gender. Work situations of Rural Women in the South of Spain

open access: yesQualitative Research in Education, 2016
Even though undeniable social changes such as gender discrimination have occurred, the forms of access to public education and employment, as well as the conditions under which these jobs are carried out, are often loaded with sexist biases.Using the ...
Magdalena Suárez-Ortega
doaj   +1 more source

Public Employment Services and Strategic Action towards Rural NEETs in Mediterranean Europe

open access: yesSocial Sciences, 2023
The NEET phenomenon in southern Europe is particularly alarming. Most studies have focused on analysing the socio-demographic characteristics of NEET and policies directed towards them, but more research is needed regarding the psychological aspects that
Daniela Marzana   +8 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Public Sector employment in Scotland [February 2012] [PDF]

open access: yes, 2012
Some 300,000 public sector workers in Scotland participated in the UK wide public sector strike at the end of November 2011, in response to plans to change pension arrangements, pension links to the CPI, retirement age and contributions.
Lockyer, Cliff
core   +3 more sources

Determining Inter-sectoral Linkages in the Iranian Economy using Extraction Method [PDF]

open access: yesپژوهشهای اقتصادی, 2013
The purpose of this study is to find the key Iranian sectors in terms of output and employment. This research is done based on the Input-Output table of the year 2001 and Extraction Method.
Mohammadgholi Yousefi
doaj  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

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