Results 111 to 120 of about 11,703,772 (300)
Advanced Science, EarlyView.Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li +21 more
wiley +1 more source
IFI27 and BAX are Essential for GSDME‐Mediated Myeloma Cell Pyroptosis
Advanced Science, EarlyView.The proposed model of GSDME‐mediated MM cell pyroptosis modulated by IFI27 and BAX. IFI27 is downregulated in MM cells. Upon pyroptotic stimulation, such as DOX or ETO treatment, IFI27 is induced, therefore liberating BAX from BCL‐2 ❶. BAX is then recruited to mitochondria and forms homo‐oligomeric channels in OMM, therefore leading to cytochrome C ...
Yaoli Cui +12 more
wiley +1 more source
, 2014 Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed Nov. 7, 2011).; At head of title: State of Connecticut.; Official website of the Connecticut State Elections Enforcement Commission.
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Law enforcement and public mental health [PDF]
Journal of Psychiatric and Mental Health Nursing, 2020 Amy Watson, Inga Heyman, Stuart Thomas
openaire +2 more sources
Learning Work Function via Implicit Reasoning on Electrostatic Potential Landscapes
Advanced Science, EarlyView.StructPot‐CLR establishes a cross‐modal contrastive learning framework that aligns the crystal structures of 2D materials with plane‐averaged electrostatic potential landscapes for physically informed work‐function prediction. The model achieves an MAE of 0.265 eV and an R2 of 0.902 on the held‐out test set while accurately preserving key morphological
Haoyu Wan, Yue Wu, Tianhao Su, Deng Pan
wiley +1 more source
Campus Law Enforcement and Public Relations [PDF]
, 2018 Law enforcement today faces challenges that are not new to this profession but are now advertised almost immediately on social media sites. This is true especially if the interaction with law enforcement is newsworthy.
Saccio, Marisa
core +1 more source
Advanced Science, EarlyView.A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li +9 more
wiley +1 more source
, 2013 Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed Nov. 7, 2011).; At head of title: State of Connecticut.; Official website of the Connecticut State Elections Enforcement Commission.
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Advanced Science, EarlyView.STWave transforms massive microscopic‐resolution spatial transcriptomics into interpretable fine‐scale tissue maps through patch‐wise inference, wavelet‐based multi‐scale encoding, and dual‐domain reconstruction. It reduces noise while preserving weak spatial signals, enabling efficient analysis of 6 40 000 spots of 2.47 GB GPU memory and revealing ...
Tao Jiang +9 more
wiley +1 more source
Do depositors care about enforcement actions? [PDF]
Since 1990, federal bank supervisors have publicly announced formal enforcement actions. This change in regime provides a natural laboratory to test two propositions: (1) claims by economists that putting confidential supervisory information in the ...
R. Alton Gilbert, Mark D. Vaughan
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