Results 141 to 150 of about 12,141,356 (259)

Niche‐Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids

Advanced Science, EarlyView.
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen, Liangxia Jiang, Xianbin Wang, Lili Zhong, Rongcan Luo, Min Su, Liangzhao Chu, Peng Luo   +7 more
wiley   +1 more source

Tax Expenditures, the Size and Efficiency of Government, and Implications for Budget Reform [PDF]

One possible explanation for the difficulty in controlling the budget is that a major component of spending —tax expenditures—receives privileged status. It is treated as tax cuts rather than spending.
Marvin Phaup, Leonard E. Burman
core  

Availability and Access to Orphan Drugs for Rare Cancers in Bulgaria: Analysis of Delays and Public Expenditures. [PDF]

Cancers (Basel)
Kostadinov K, Popova-Sotirova I, Marinova Y, Musurlieva N, Iskrov G, Stefanov R.   +5 more
europepmc   +1 more source

A Scalable Spin‐Coating Strategy for Mesoporous Gold Thin Films toward miRNA Detection

Advanced Science, EarlyView.
A scalable spin‐coating strategy produces uniform mesoporous Au thin films with tunable thickness and high electroactive surface area on transparent substrates. The resulting architecture enables label‐free, amplification‐free detection of ovarian cancer‐associated miRNA hsa‐miR‐200c‐3p from 1 aM to 10 pM, achieving a 1.72 aM detection limit with high ...
Aditya Ashok, Emtiaz Ahmed, Arya Vasanth, Mandy Hei Man Leung, Miharu Eguchi, Md Shahriar A. Hossain, Mostafa Kamal Masud, Carlos Salomon, Yusuke Yamauchi   +8 more
wiley   +1 more source

Spatial Interaction and Local Government Expenditures for Functionally Impaired in Sweden [PDF]

The thesis consists of an introductory part and three self-contained papers. Paper [I] studies the determinants of the differences in expenditure on services for functionally impaired individuals among municipalities in Sweden.
Birkelöf, Lena
core  

Sex‐ and Time‐Resolved Physiological and Gut Ecosystem Responses to a Food‐Grade Microbiome‐Targeted Intervention in Collegiate Endurance Athletes

Advanced Science, EarlyView.
In collegiate endurance athletes, a 6‐week randomized CPYE intervention yielded time‐ and sex‐dependent shifts in field‐based cardiorespiratory, metabolic, and redox indices, accompanied by changes in gut multi‐omics profiles. An exploratory extension during intensified training generates hypotheses warranting future validation.
Meng Zhang, Le Ge, Kaiyang Liu, Yanrong Liu, Guolin Zhao, Lai‐Yu Kwok, Zheng Sun, Zhihong Sun, Wenyi Zhang   +8 more
wiley   +1 more source

Public Finances and Economic Transition [PDF]

This paper analyzes developments in general government expenditures and revenues for 26 reforming ex-socialist economies (RESEs) over the period 1989-1994.
Hana Polackova, Luca Barbone
core  

Pharmaceutical Industry Pay-Per-Click Advertising Strategies to Influence Public Opinions on Drug Pricing. [PDF]

Clin Pharmacol Ther
Eisenkraft Klein D, Kesselheim AS.
europepmc   +1 more source

Structural Divergence Between the Moltbook AI‐Agent Network and Human Social Networks

Advanced Science, EarlyView.
Analysis of the Moltbook AI‐agent network reveals a striking combination of familiar global scaling and distinct internal organization. Attention is highly concentrated, reciprocity is limited, connected triads are suppressed, and communities are strongly modular.
Wenpin Hou, Zhicheng Ji
wiley   +1 more source

Healthcare costs of childhood overweight and obesity in Chile: evidence from an analysis of linked administrative records. [PDF]

J Glob Health
Valdés N, Abufhele A, Vega A, Borrescio-Higa F.   +3 more
europepmc   +1 more source