Results 161 to 170 of about 73,712 (259)

Is health financing converging in the European Union? Nonlinear dynamics and policy implications for non-euro area member states. [PDF]

Front Public Health
Dritsaki M, Dritsaki C, Sarigiannidis P, Genni AG.   +3 more
europepmc   +1 more source

NSD2 Coordinates the Neurogenic‐to‐Gliogenic Transition via H3K36me2‐Dependent Activation of the EGFR‐ERK Pathway

Advanced Science, EarlyView.
NSD2 coordinates the neurogenic‐to‐gliogenic transition in the developing neocortex through H3K36me2‐dependent activation of EGFR–ERK signaling. Loss of NSD2 disrupts astroglial and oligodendroglial development, whereas ERK activation rescues gliogenic defects in vitro and in vivo.
Hanxue Chen, Mengyuan Li, Lin Hou, Bin Yin, Boqin Qiang, Ran Gao, Pengcheng Shu, Xiaozhong Peng   +7 more
wiley   +1 more source

Hydrogen‐Bonding‐Directed Assembly of COF/Nanocluster Hybrids With Synergistic Roles for Efficient Solar Hydrogen Production

Advanced Science, EarlyView.
Hydrogen‐bonding‐directed assembly enables molecular‐level integration of a covalent organic framework and NiZnCo nanoclusters. The engineered interface couples directional charge transfer, multimetal synergy, and photothermal‐assisted catalysis, providing a versatile strategy for efficient noble‐metal‐free solar hydrogen production.
Ailing Pan, De Yan, Anwu Xu, Hong Du, Abulikemu Abudu Rexit, Gang Zhang   +5 more
wiley   +1 more source

Temporal Patterns of Breast Cancer-Related Sickness Absence and Social Insurance Expenditures Among Women in Poland, 2020-2024: A Nationwide Registry-Based Study. [PDF]

Curr Oncol
Winciunas PA, Grudziąż-Sękowska J, Mazurek A, Sękowski K, Zgliczyński WS, Jankowski M.   +5 more
europepmc   +1 more source

A Second Pathogenic Protein, PolyGN2C‐iso2, Reveals a Dual‐Protein Pathology in Neuronal Intranuclear Inclusion Disease

Advanced Science, EarlyView.
This study reveals that NOTCH2NLC transcript variant 2 generates PolyGN2C‐iso2, an aggregating protein present within intranuclear inclusions of NIID patient tissues. A novel mouse model expressing PolyGN2C‐iso2 recapitulates white matter abnormalities and cognitive deficits, mechanistically linked to mitochondrial dysfunction. These findings support a
Kang Zhang, Wenhao Ma, Yi Zhou, Zhijie Wu, Pan Gao, Hongze Niu, Hongfei Tai, Tianyi Zhao, Zheyue Dong, Li Li, Yan Zhang, An Wang, Si Shen, Yueyang Li, Sifei Yu, Yan Peng, Wang Sheng, Xiaoyan Dong, Hua Pan, Kaibin Shi, Magdalena J. Koziol, Xiaobing Wu, Zaiqiang Zhang   +22 more
wiley   +1 more source

Estimating the distributional impact of improving access to snake antivenom in urban and rural Lao People's Democratic Republic: An extended cost-effectiveness analysis. [PDF]

PLoS Negl Trop Dis
Patikorn C, Khuharatanachai T, Cho JY, Taychakhoonavudh S, Mayxay M, Senbounsou K, Blessmann J, Chaiyakunapruk N.   +7 more
europepmc   +1 more source

Agent‐Based Simulations of Lung Tumor Evolution Suggest That Ongoing Cell Competition Drives Realistic Clonal Expansions

Advanced Science, EarlyView.
Computational simulations of tumor evolution are increasingly used to infer the rules underlying cancer growth, with the goal of one day recommending tailored treatments. Here we show that the properties of lung cancer sequencing data are best replicated by a model which assumes that cells compete both to proliferate and survive. ABSTRACT Computational
Helena Coggan, James R. M. Black, Carlos Martínez‐Ruiz, Kristiana Grigoriadis, Jasmin Fisher, Nicholas McGranahan   +5 more
wiley   +1 more source

Changes in tobacco sales before, during, and after the COVID-19 pandemic in Japan: An interrupted time series analysis. [PDF]

PLoS One
Kondo K, Morita I, Sakuma S, Ohsawa I.
europepmc   +1 more source

CLRe: A Synergistic Dual‐Engine Framework for One‐Step Retrosynthesis Prediction

Advanced Science, EarlyView.
CLRe uses a contrastive difficulty score to order pretrained seq2seq fine‐tuning for retrosynthesis. Reaction embeddings define the ranking score, and a cumulative easy‐to‐hard schedule expands from the easiest subset to the full training set while earlier examples remain active.
Tianhao Su, Xitao Wang, Musen Li, Guanhua Qin, Shunbo Hu, Tong‐Yi Zhang   +5 more
wiley   +1 more source

The price of equality: determinants of the convergence in delivery costs in Bangladesh. [PDF]

Front Public Health
Fischer M, Ali M, Saha S.
europepmc   +1 more source