Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Pengaruh Kebijakan Dividen dan Investment Opportunity Set (IOS) terhadap Kinerja Perusahaan pada Perusahaan BUMN Go Public [PDF]
This research to determine the effect of devidend policy and Investment Opportunity Set (IOS) on the firm performance on state-owned enterprises (SOE) go public listed in the Indonesia Stock Exchange.
Anggi Angga Resti +2 more
doaj +3 more sources
Public Servants: a Competitive Advantage for Public Firms? [PDF]
In many of the deregulated markets of the EU, incumbent firms compete with new entrants. Incumbent firms may have public servants on their payroll. We investigate the cost and benefit of public servant employment, and present a simple model that shows that payroll taxes for public servants are in equilibrium smaller than the ones for workers with ...
Friebel, Guido, Magnac, Thierry
openaire +3 more sources
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Lifetime Employment and a Sequential Choice in a Mixed Duopoly Market with a Joint-Stock Firm [PDF]
This paper examines a three-stage game model in which a joint-stock private firm and a state-owned public firm can sequentially offer lifetime employment before competing in quantities. The game runs as follows.
Kazuhiro Ohnishi
doaj
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Reaction Functions under Quantity Competition in International Mixed Triopolies [PDF]
This paper considers an economy in which a state-owned public firm, a domestic private firm and a foreign private firm compete in output levels. The paper examines the firms’ reaction functions in the economy.
Kazuhiro Ohnishi
doaj
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Industry-science connections in agriculture: Do public science collaborations and knowledge flows contribute to firm-level agricultural research productivity? [PDF]
Prior research shows long-run productivity growth in agriculture is associated with increases in the stock of public scientific knowledge and private patented inventions. However, private inventions may be a function of the stock of public knowledge.
King, John L., Toole, Andrew A.
core +2 more sources

