Results 81 to 90 of about 11,933,057 (302)
The Marginal Cost of Public Funds is One [PDF]
This paper develops a Mirrlees (1971) framework with heterogeneous agents to analyze optimal redistributive taxes, optimal provision of public goods and the marginal cost of public funds (MCF). Standard MCF measures are shown to suffer from three defects:
Jacobs, Bas
core
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
On the relationship of funding and research publications [PDF]
Scientometrics, 1991 The impact of 17 year period of funding in schistosomiasis research on publication outcome was examined. Two productivity and three quality indicators were used to compare the output from the entire population of schistosomiasis in this period with those associated with 351 funded researchers.
openaire +5 more sources
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
State and Service Estimates of Substance Use Treatment Facilities That Receive Public Funds in the United States. [PDF]
Subst Abuse Rehabil, 2023 Ware OD.
europepmc +1 more source
Structural and cohesion funds, a financing alternative for romanian public administration [PDF]
In conditions of economic stability and, even more so, in conditions of crisis, when the budgetary resources are subjected to additional stress, public administration has an alternative financing source, by means of accessing the structural and cohesion ...
DANA MIHAELA MURGESCU
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
The Impact of European Funds on Public Expenditure in Poland
Zeszyty Naukowe Uniwersytetu Ekonomicznego w Krakowie, 2018 The main purpose of the study is to evaluate the impact of European funds on the level and structure of public expenditure in Poland. Basically, the research period covers the years 2000–2016.
Alina Klonowska
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source