Results 101 to 110 of about 16,344,347 (304)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Report of the Council of the University of the Cape of Good Hope nineteen hundred and seven
, 2015 Report of the proceedings of the University of the Cape of Good Hope during 1907.Official 1907 Report of the Council of the University of the Cape of Good Hope to the Cape Colonial Parliament.
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IT’S ALL GOOD—BUT FOR WHOM? EXAMINING THE PRESENCE OF PUBLIC GOOD WITHIN DISSERTATIONS FROM PUBLIC RESEARCH INSTITUTIONS [PDF]
, 2018 The purpose of this exploratory research project is to explore if university research extends “beyond the walls” of research universities and seeks to address the social matters relevant to the greater community.
Scruggs, Yashanda
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Frontiers in Energy Research, 2016 To solve problems like climate change, every little push counts. Community energy schemes are a popular policy targeted to reduce a country’s carbon emissions but the effect they have on energy use depends on whether people can work together as a ...
Anya eSkatova +4 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Report of the Council of the University of the Cape of Good Hope nineteen hundred and eight
, 2015 Report of the proceedings of the University of the Cape of Good Hope during 1908.Official 1908 Report of the Council of the University of the Cape of Good Hope to the Cape Colonial Parliament.
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Report of the Council of the University of the Cape of Good Hope nineteen hundred and six
, 2015 Report of the proceedings of the University of the Cape of Good Hope during 1906.Official 1906 Report of the Council of the University of the Cape of Good Hope to the Cape Colonial Parliament.
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Deliberative leadership: Sustainable practices for public universities?
JPHEThe higher education landscape is experiencing a period of serious uncertainty, an interregnum wherein there is considerable disagreement as to its orientation and sustainability.
Ciaran Sugrue, Tone Dyrdal Solbrekke
doaj +1 more source