Results 101 to 110 of about 1,303,116 (264)
Political ideology and moral dilemmas in public good provision. [PDF]
Sci Rep, 2023 Hoenig LC, Pliskin R, De Dreu CKW.
europepmc +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Vaccines: A universal public good. [PDF]
Med Clin (Engl Ed), 2022 Padrós Selma J.
europepmc +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Restoration of Lighthouse Facilities and their Valorisation through Commercial Activities
Ekonomski Vjesnik, 2010 There have not been many studies on the role of lighthouses throughout history. Since the lighthouse has become a prototypical example of a good market solution for the public goods problem, there is a high demand for these studies. The authors develop
Mate Perišić +2 more
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Evolution of toxins as a public good in phytoplankton. [PDF]
Proc Biol Sci, 2022 Ehrlich E, Thygesen UH, Kiørboe T.
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Competition among public good providers for donor rewards. [PDF]
Exp Econ, 2022 Struwe N, Blanco E, Walker JM.
europepmc +1 more source