Results 81 to 90 of about 6,596,047 (309)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Intellectual property as intangible good
Ekonomia i Prawo, 2019 Motivation: Nowadays in economic literature we can observe the increasing popularity of the concept of intellectual property. Nevertheless, this growth is not accomplished by solving conceptual problems. The number of existing definitions, considerations
Dominika Bochańczyk-Kupka
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Epidemiology, Biostatistics and Public Health, 2019 Background: Adverse events following immunization are a major concern which is influencing vaccination coverage all over the world. It is therefore important to evaluate the reporting of this events and factors associated with their occurrence in order ...
Irsida Mehmeti +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Games, 2011 This paper provides experimental evidence on how players predict end-game effects in a linear public good game. Our regression analysis yields a measure of the relative importance of priors and signals on subjects’ beliefs on contributions and allows us ...
Maria Paz Espinosa, Pablo Brañas-Garza
doaj +1 more source
Response to Privacy as a Public Good [PDF]
, 2016 In the spirit of moving forward the theoretical and empirical scholarship on privacy as a public good, this response addresses four issues raised by Professors Fairfield and Engel’s article: first, their depiction of individuals in groups; second ...
Regan, Priscilla M.
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Authors’ response to Ashley Roberts’ letter to the editor on aspartame and cancer
Environmental Health, 2021 Philip J. Landrigan, Kurt Straif
doaj +1 more source
Agricultural Economics (AGRICECON), 2007 The paper seeks to analyse the understanding of food safety by consumers of agro food products in the Nitra region. The food safety is here understood as the complex of precautions concerning the plant health protection, veterinary problems, animal ...
R. Serenčéš, M. Rajčániová
doaj +1 more source