Results 71 to 80 of about 16,344,347 (304)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Report of the Council of the University of the Cape of Good Hope eighteen ninety five
, 2015 Report of the proceedings of the University of the Cape of Good Hope during 1895.Official 1895 Report of the Council of the University of the Cape of Good Hope to the Cape Colonial Parliament.
core
Zbornik Znanstvenih Razprav, 2016 In the UK, private policing institutions have been rapidly increasing since the 1980s, so the lines between public- and private police have been blurred.
Jasmina Arnež
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Report of the Council of the University of the Cape of Good Hope eighteen ninety eight
, 2015 Report of the proceedings of the University of the Cape of Good Hope during 1898.Official 1898 Report of the Council of the University of the Cape of Good Hope to the Cape Colonial Parliament.
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Report of the Council of the University of the Cape of Good Hope nineteen hundred
, 2015 Report of the proceedings of the University of the Cape of Good Hope during 1900.Official 1900 Report of the Council of the University of the Cape of Good Hope to the Cape Colonial Parliament.
core
Threat and Punishment in Public Good Experiments [PDF]
Experimental studies of social dilemmas have shown that while the existence of a sanctioning institution improves cooperation within groups, it also has a detrimental impact on group earnings in the short run.
Villeval, Marie Claire +2 more
core +4 more sources
THE REGULATION OF PUBLIC GOODS
Journal of International Economic Law, 2004 The paper examines the complex ways in which public goods are regulated. The provision and distribution of public goods is deeply affected by the degree of excludability of those goods and the regulatory context of that excludability. Using a decentered conception of regulation, the paper shows through various examples how state and non-state actors ...
openaire +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source