Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
From public health to public good: Toward universal wellbeing. [PDF]
Heimburg DV +3 more
europepmc +1 more source
Public, private, and the appeal to common good: Practices of justification in a peer‐to‐peer economy [PDF]
Regan Koch
openalex +1 more source
State Reputation as a Public Good [PDF]
A state’s concern for its reputation is widely considered the most powerful mechanism for inducing rational egoist states to comply with costly commitments. A state with a diversity of interests will accept costs on organised groups in the expectation of
William Phelan
core
Definiranje pojma javno dobro : Definition of Term Public Good [PDF]
In the article the term public good is discussed, as well as the problems related to the definition of the term, the reasons for these problems, possible solutions and actors that could contribute to solving these problems.
Marijana Vugrin
doaj
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Moving beyond dashboards to generate data for public good-Authors' reply. [PDF]
Yadav CP, Sharma A.
europepmc +1 more source
Country size and public good provision [PDF]
The paper studies the equilibrium size of countries. Individuals in small countries have greater influence over the nature of political decision making while individuals in large countries have the advantage of more public goods and lower tax rates.
K Staal
core
Restoration of Lighthouse Facilities and their Valorisation through Commercial Activities
There have not been many studies on the role of lighthouses throughout history. Since the lighthouse has become a prototypical example of a good market solution for the public goods problem, there is a high demand for these studies. The authors develop
Mate Perišić +2 more
doaj
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source

