Results 171 to 180 of about 16,262,576 (403)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Private Provision of a Complementary Public Good [PDF]

For several years, an increasing number of firms have been investing in Open Source Software (OSS). While improvements in such a non-excludable public good cannot be appropriated, companies can benefit indirectly in a complementary proprietary segment ...
Richard Schmidtke
core   +3 more sources

Social distancing as a public-good dilemma for socio-economic cost: An evolutionary game approach. [PDF]

Heliyon, 2022
Ovi MA, Nabi KN, Kabir KMA.
europepmc   +1 more source

Brokerage as a Public Good: The Externalities of Network Hubs for Different Formal Roles in Creative Organizations

, 2018
J. Clement, A. Shipilov, C. Galunic
semanticscholar   +1 more source

Higher Education as a public good: pushing forward, pushing boundaries [PDF]

, 2012
This paper reports on a project which has embedded Open Educational Resources (OER) into the teaching and learning of students who are undertaking professional degrees in social work and nursing.
Crawford, Karin, Mathews, Ian, Simpson, Diane   +2 more
core  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Public good-driven release of heterogeneous resources leads to genotypic diversification of an isogenic yeast population. [PDF]

Evolution, 2022
Mahilkar A, Nagendra P, Alugoju P, E R, Saini S.   +4 more
europepmc   +1 more source

Nursing Home Quality as a Public Good [PDF]

There has been much debate among economists about whether nursing home quality is a public good across Medicaid and private-pay patients within a common facility. However, there has been only limited empirical work addressing this issue.
David C. Grabowski, Jonathan Gruber, Joseph J. Angelelli   +2 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

IS AGRICULTURAL RESEARCH STILL A PUBLIC GOOD? [PDF]

The nature of public agricultural research changed in 1980 when the Bayh-Dole Act allowed universities to retain title to inventions that were created with Federal funds, and the court case Diamond v.
Hightower, Amie L., Maredia, Mywish K., Naseem, Anwar, Oehmke, James F., Weatherspoon, Dave D., Wolf, Christopher A.   +5 more
core   +1 more source