Results 61 to 70 of about 1,004,415 (240)

THE LIMITATIONS IN PUBLIC HEALTH ADMINISTRATION [PDF]

Journal of the American Medical Association, 1909
A potent cause of unsatisfactory results in public health work is found in the vague ideas often entertained among officials, private physicians and the people generally, relative to the powers and duties of health departments. There is often a clearer perception of the object to be attained than of the means to that end.
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

What Can Public Health Administration Learn from the Decision-Making Processes during COVID-19? [PDF]

Int J Environ Res Public Health, 2023
Joyce A, Risely E, Green C, Carey G, Buick F.   +4 more
europepmc   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Study on patient perception on digital health platforms in Delhi National Capital Region

Discover Public Health
The increasing integration of digital health technologies within healthcare systems necessitates a comprehensive understanding of patient perceptions. A quantitative, cross-sectional survey approach is employed, using inferential statistical analysis to ...
Bhawna Sharma, A. Bhoomadevi, Amrish Chandra   +2 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Factors associated with Traditional Chinese Medicine use among older adults with chronic diseases in China

Scientific Reports
Chronic diseases impose a substantial health and economic burden in China, particularly among its rapidly aging population. Traditional Chinese Medicine (TCM) has been integrated into primary healthcare through national policies and is considered a ...
Xuexia Gao, Hui Huang, Dequan Shen, Dahui Wang, Rouyi Xu, Chenxuan Gong, Yan Chen   +6 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Social capital, health status, and sociodemographic factors associated with subjective well-being among older adults: a comparative study of community dwellings and nursing homes

BMC Public Health
Background This study aimed to examine the differences in relationships among social capital components, health status, sociodemographic characteristics, and subjective well-being (SWB) among older adults in institutionalized versus non-institutionalized
Yan Chen, Dahui Wang, Wenhao Chen, Enxi Zhao, Wanjing Li, Shanshan Zhu, Xianlan Wu   +6 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source