Results 71 to 80 of about 3,011,326 (280)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Strategic planning and organizational performance in public health sector: a scoping review

BMC Health Services Research
Background Strategic planning is a methodical approach to generate fundamental decisions and actions that influence and direct the nature, function, and rationale of the public health sector. However, the existing literature presents mixed findings. This
Utoomporn Wongsin, Tanavij Pannoi, Chardsumon Prutipinyo, Mohammad Ainul Maruf, Dichapong Pongpattrachai, Orawan Quansri, Youwanuch Sattayasomboon   +6 more
doaj   +1 more source

The public health benefit and burden of mass drug administration programs in Vietnamese schoolchildren : impact of mebendazole [PDF]

, 2018
Background: Mass anthelmintic drug administration is recommended in developing countries to address infection by soil-transmitted helminthiases (STH).
De Smedt, Delphine, Debaveye, Sam, Dewulf, Jo, Gonzalez Torres, Claudia Virginia, Heirman, Bert, Kavanagh, Shane   +5 more
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Struggling to a monumental triumph : Re-assessing the final stages of the smallpox eradication program in India, 1960-1980 [PDF]

, 2007
The global smallpox program is generally presented as the brainchild of a handful of actors from the WHO headquarters in Geneva and at the agency's regional offices.
Basu, R. N, Bonne W, Bonne W, Brilliant L. B, Brilliant L. B, Dutta Mahendra, Dutta Mahendra, Grasset N, Grasset N, Grasset N, Grasset N, Grasset N, Grasset N. c, Greenough P, Gunaratne V.T.H, Henderson D.A, Henderson D.A, Henderson D.A, Henderson D.A, Henderson D.A, Henderson D.A, Henderson D.A, Henderson D.A, Henderson D.A, Henderson D.A, Jungalwalla N.K, Mahler H, Maltseva N, Mani C, Naraindas Harish, Payne A.M.H, Pifer John M, Sanjoy Bhattacharya, Singh Mahendra   +33 more
core   +2 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Social capital, health status, and sociodemographic factors associated with subjective well-being among older adults: a comparative study of community dwellings and nursing homes

BMC Public Health
Background This study aimed to examine the differences in relationships among social capital components, health status, sociodemographic characteristics, and subjective well-being (SWB) among older adults in institutionalized versus non-institutionalized
Yan Chen, Dahui Wang, Wenhao Chen, Enxi Zhao, Wanjing Li, Shanshan Zhu, Xianlan Wu   +6 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Evaluation of the Utilization of the Hospital Management Information System (SIMRS) at Madani Regional General Hospital, Palu

Journal of Public Health and Pharmacy
Introduction: The Hospital Management Information System (SIMRS) plays a crucial role in supporting optimal healthcare services in hospitals. SIMRS enables efficient and effective management of information, ranging from patient data to hospital ...
Muhammad Rifial, Amran Razak, Darmawansyah Darmawansyah, Indar Indar, Arsyad Rahman   +4 more
doaj   +1 more source

What Can Public Health Administration Learn from the Decision-Making Processes during COVID-19? [PDF]

Int J Environ Res Public Health, 2023
Joyce A, Risely E, Green C, Carey G, Buick F.   +4 more
europepmc   +1 more source