Results 71 to 80 of about 3,015,723 (281)
BMC Family Practice, 2019 Background Developed countries have widely implemented a gatekeeping system as a core policy of primary care, also known as the system of first visit in the community.
Cuiying Liang +5 more
doaj +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Through Mintzberg’s glasses: a fresh look at the organization of ministries of health
Bulletin of the World Health Organization, 2000 In 1987, district health care policies were officially adopted by a majority of developing countries. Many operational problems constraining implementation of such policies have subsequently been identified, most of which are attributable to well-known ...
Jean-Pierre Unger +3 more
doaj
Factors associated with the acceptance of telemedicine services in Dusit model prototype area
Scientific ReportsThe Dusit Model, a prototype area in Bangkok, Thailand, integrates telemedicine into primary and tertiary care to reduce overcrowding and promote equitable access. This study aimed to identify factors influencing telemedicine acceptance using an extended
Nontawat Benjakul +3 more
doaj +1 more source
Health Care for Veterans: Suicide Prevention [PDF]
, 2016 [Excerpt] Congress has attempted to address the problem of suicide among veterans through legislation and oversight hearings, both on prevention of veteran suicide specifically and on veteran mental health more broadly.
Bagalman, Erin
core +3 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
The impact of public leadership on collaborative administration and public health delivery
BMC Health Services ResearchBackground This research depicts the linkage of public leadership on public health delivery (PHD) and collaborative administration. The research is also focused to examine the effect of public leadership on public health delivery through the intervening ...
Muhammad Zia ud din +3 more
doaj +1 more source
Social Equity and COVID-19: The Case of African Americans [PDF]
, 2020 Emerging statistics demonstrate that COVID-19 disproportionately affects African Americans. The effects of COVID-19 for this population are inextricably linked to areas of systemic oppression and disenfranchisement, which are further exacerbated by COVID-
Merritt, Cullen C., Wright, James E.
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