Results 91 to 100 of about 5,645,039 (315)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

A Functional Public Health Surveillance System

American Journal of Public Health, 2012
Lenert and Sundwall identify opportunities and challenges of the Meaningful Use (MUse) incentive programs that advance standardized electronic reporting to health departments at a time when there is limited funding to upgrade systems. We concur that cloud-based Platform as a Service (PaaS) is a possible remedy.
Taha A, Kass-Hout, Kathleen, Gallagher, Seth, Foldy, James W, Buehler   +3 more
openaire   +3 more sources

Movement and dietary behaviours and mental health among university students: the Health@NUS study

BMC Public Health
Introduction University years represent a crucial period in a student’s life, with mounting pressures on mental health and the formation of lifestyle habits that may endure into adulthood. This study examined the associations between movement and dietary
Shenglin Zheng, Xin Hui Chua, Sarah Martine Edney, Claire Marie Goh, Bee Choo Tai, Janelle Chia, Daphne Koek, Rob M. van Dam, Falk Müller-Riemenschneider   +8 more
doaj   +1 more source

Perceived satisfaction of prenatal care among women without social security: comparative qualitative analysis between individual and group care models in Mexico

BMJ Open
Background The inadequate handling of obstetrical complications may be attributed to the suboptimal quality of prenatal care (PC) and a lack of trust in healthcare provider (HP) among pregnant women.Objective This study explores the perceptions of ...
Blair Darney, Jacqueline Elizabeth Alcalde-Rabanal, Miriam Rosario Santivañez Salazar, Ileana Beatriz Heredia-Pi, Lourdes Campero   +4 more
doaj   +1 more source

Ex Post Welfare under Alternative Health Care Systems [PDF]

This paper studies the implications of a societal aversion to inequality for the optimal design of a public health care system. Inequality aversion is introduced by postulating a strictly concave ex post social welfare function.
John Leach
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Strengthening Public Health Systems

, 2020
Public health systems that are capable of disease surveillance and action to prevent and manage outbreaks require trustworthy community-embedded public health workers who are empowered to undertake their tasks as professionals.
Khemani, Stuti, Chaudhary, Sarang, Scot, Thiago   +2 more
openaire   +1 more source

The Epidemics of Injecting Drug Use and Blood-Borne Disease: A Public Health Perspective [PDF]

, 1997
In this article, the author first examines the mechanism by which blood-borne disease is transmitted through sharing of injection equipment. Thereafter, he presents a public health strategy for reducing multi-person use of contaminated injection ...
Gostin, Lawrence O.
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source