Results 121 to 130 of about 5,706,223 (363)

Validation of the consumer health activation index (CHAI) among community-dwelling adults in primary care clinics in Singapore

Population Health Metrics
Background Health activation is an individual’s knowledge, skills, and confidence in managing personal health and healthcare. The Consumer Health Activation Index (CHAI) is a freely available, 10-item measure originally developed in the United States ...
Justin Guang Jie Lee, Qin Xiang Ng, Nan Luo, Gerald Choon Huat Koh, Ling Jie Cheng   +4 more
doaj   +1 more source

Young Adult Outcomes of Youth Exiting Dependent or Delinquent Care in Los Angeles County [PDF]

, 2011
Compares educational, employment, health, mental health, criminal justice, and public welfare outcomes for youth who age out of foster care, those who exit the juvenile probation system, and those who were involved in both systems.
Dennis P. Culhane, Halil Toros, Manuel Moreno, Max Stevens, Stephen Metraux, Thomas Byrne   +5 more
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Association of a healthy ageing index with health-related outcomes in a multi-ethnic cohort from Singapore

BMC Geriatrics
Background The global population is ageing rapidly and it is important to promote healthy ageing. The Healthy Ageing Index (HAI) is a comprehensive measure of health, but there is limited research on its association with other age-related outcomes.
Nazira Binte Muhammad Fauzi, Xiangyuan Huang, Ling Jie Cheng, Nan Luo, Saima Hilal   +4 more
doaj   +1 more source

Public and Private Health Insurance in Germany: The Ignored Risk Selection Problem [PDF]

While risk selection within the German public health insurance system has received considerable attention, risk selection between public and private health insurers has largely been ignored.
Martina Grunow, Robert Nuscheler
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Public Health Medicine, Public Health Practice, and Public Health Systems [PDF]

Canadian Journal of Public Health, 2013
openaire   +2 more sources

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Cost-Effectiveness Of Mycophelonate Sodium On Patients With Renal Transplant At The Public Mexican Health Care System [PDF]

, 2014
Miranda C.I. Ruiz, Lopez V. Ubiarco
openalex   +1 more source