Results 131 to 140 of about 5,706,223 (363)

Governance of communicable disease control services : a case study and lessons from India [PDF]

open access: yes
The authors study the impact of governance and administrative factors on communicable disease prevention in the Indian state of Karnataka using survey data from administrators, frontline workers, and elected local representatives.
Das Gupta, Monica   +2 more
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Partnership-based sexual behaviours among adults in Singapore: a cross-sectional population survey

open access: yesBMJ Public Health
Introduction Sexual behaviour data are essential for monitoring sexual behavioural trends and designing effective sexual health interventions. In Singapore and other Southeast Asian countries, where research has largely focused on key populations, this ...
Kiesha Prem   +8 more
doaj   +1 more source

Transparency and Public Reporting Are Essential for a Safe Health Care System [PDF]

open access: yes, 2010
Compares three approaches to spurring hospitals to improve patient safety and argues that public reporting of performance and feedback to providers is more effective than regulation and accreditation or financial ...
Lucian L. Leape
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Choosing Health Insurance in a Dual Health Care System: The Chilean Case [PDF]

open access: yes
In Chile there is a public insurance system where people contribute a fixed percentage of their income, and also a private system where people pay a premium based on their personal characteristics. Using a large survey for 1996, we study the determinants
Jaime Ruiz-Tagle, Ricardo Sanhueza
core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Parallel Private Health Insurance in Australia: A Cautionary Tale and Lessons for Canada [PDF]

open access: yes
Canada's restrictions on the role of private health insurance for publicly insured physician and hospital services are unique among countries with universal, publicly funded health care systems.
Deborah Cobb-Clark   +3 more
core  

No. 54: Medical Xenophobia: Zimbabwean Access to Health Services in South Africa [PDF]

open access: yes, 2011
Medical xenophobia refers to the negative attitudes and practices of health sector professionals and employees towards migrants and refugees on the job.
Crush, Jonathan, Tawodzera, Godfrey
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

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