Results 121 to 130 of about 5,489,322 (308)
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Resenha do livro MAUAD, Ana Maria; SANTIAGO, Ricardo; BORGES, Viviane Trindade. Que história pública queremos?: What Public History do we want? São Paulo: Letra e Voz, 2018.
openaire +1 more source
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
University Scholar Series: Alison McKee [PDF]
The Woman’s Film of the 1940s: Gender, Narrative, and History On February 25, 2015, Dr. Alison L. McKee spoke in the University Scholar Series hosted by Provost Andy Feinstein at the Dr. Martin Luther King, Jr. Library. Dr.
McKee, Alison L.
core +1 more source
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
A Independência e uma cultura de história no Brasil
Resumo O objetivo deste artigo é propor uma análise preliminar de atitudes e valores que os brasileiros da atualidade nutrem diante de um fato histórico específico - a Independência do Brasil - bem como refletir acerca das relações de tais valores e ...
João Paulo Pimenta +6 more
doaj +1 more source
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Partnerships with an Oral Historian [PDF]
Oral history research methodologies are growing in popularity as an instrument of capturing contemporary stories or voices, of the local, personal, public and the global experience.
Klaebe, Helen G.
core +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
History, Expectations, and Public Policy: Economic Development in Eastern Germany [PDF]
Motivated by the process of economic development in Eastern Germany since the German reunification we set up a dynamic macroeconomic model of a small open economy where both capital and labor are mobile and there are increasing returns to scale at the ...
Andreas Schäfer, Thomas Steger
core

