Results 101 to 110 of about 5,489,322 (308)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

“How a Democratic Country Could Become a Dictatorial Monster”: A Conversation with Volker Kutscher About His Crime Novels, Babylon Berlin, and the Lessons of the Past

International Public History
The German TV series Babylon Berlin is based on the popular crime novels by Volker Kutscher on Weimar Berlin in the 1920s. In this conversation, the author explains his ambitions to make his readers aware how a democracy can change into a dictatorship ...
Hochmuth Hanno
doaj   +1 more source

[Review of] Michi Kodama-Nishimoto, et al. Hanahana, An Oral History Anthology of Hawaii\u27s Working People [PDF]

, 1986
Oral history is unquestionably an important method for recovering the history of ethnic groups, particularly of ethnic working people who leave few written accounts of their own and whose lives are often ignored or else inadequately described by ...
Endo, Russell
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Interview with James I. Tarman, May 5, 2000

, 2000
James I. Tarman was interviewed on May 5, 2000 by Michael J. Birkner about his years as a student at Gettysburg College, Class of 1952, and becoming the school\u27s first public relations director.
Birkner, Michael J., Tarman, James I.
core  

Is There an Ethics for Historians? [PDF]

, 2009
How should historians treat one another? More generally, what are the ethical obligations that go with belonging to the profession of history? And more generally still, in what ways and in what sense is history a profession and how are professional ...
Tapper, Alan
core  

Past Visions of Artificial Futures: One Hundred and Fifty Years under the Spectre of Evolving Machines

, 2018
The influence of Artificial Intelligence (AI) and Artificial Life (ALife) technologies upon society, and their potential to fundamentally shape the future evolution of humankind, are topics very much at the forefront of current scientific, governmental ...
Dorin, Alan, Taylor, Tim
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Public History from the Global South: Contributions to the Dialogue from South and Southeast Asian Public Historians

International Public History
Three public historians from South and Southeast Asia consider the questions posed by the organizers of the Dialogue between African and Latin American public historians that feature also in this issue of the journal. We begin with the English version of
Dean David
doaj   +1 more source

Book review: Showing Resistance: Propaganda and Modernist exhibitions in Britain, 1933–53, by Dr Harriet Atkinson

Science Museum Group Journal
Scott Anthony, Deputy Head of the Research & Public History Department at the Science Museum in London, reviews Harriet Atkinson’s book Showing Resistance: Propaganda and Modernist exhibitions in Britain, 1933–53.
Scott Anthony
doaj   +1 more source