Results 91 to 100 of about 5,489,322 (308)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
The Role of New Media and Digital Narratives in Urban Planning and Community Development
Body, Space & Technology Journal, 2008 Many new urban developments are systematically planned and rapidly built and marketed, creating instant ‘communities’ in relatively dense concentrations. As a consequence, urban planners are turning to the social sciences, arts and humanities for answers
Marcus Foth, Helen Klaebe, Greg Hearn
doaj
Founding brothers: Leland, buck, and cappon and the formation of the archives profession (session 404) [PDF]
, 2011 This session on archives history examines the role of three individuals-Waldo G. Leland (1879-1966), Solon J. Buck (1884-1962), and Lester J. Cappon (1900-1981)-in the formation of the archives profession in the United States in the first three-quarters ...
Cox, RJ, Dollar, C, Hirsch, R, Wosh, PJ
core
An epidemiological study of burglary offenders: trends and predictors of self-reported arrests for burglary in the United States, 2002-2013 [PDF]
, 2016 Burglary is serious property crime with a relatively high incidence and has been shown to be variously associated with other forms of criminal behavior.
Boutwell, B. B. +4 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Union-Management Training Programs in the Public Sector: The New York Experience [PDF]
, 1991 [Excerpt] New York State has a long history of union-management education and training programs, making it unique in public sector employment. This chapter examines the programs undertaken at both state and city levels, as well as the applicability of ...
Gray, Lois Spier +2 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
2004 Water Quality Education Onboard the Gundalow, Bolster, M [PDF]
, 2004 The Gundalow Company (a non-profit 501(c)3 organization) sponsors maritime history and environmental educational programs for school groups and the public onboard the replica gundalow Captain Edward Adams from May through November in 12-15 riverfront ...
Bolster, Molly
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source