Results 181 to 190 of about 277,535 (306)

Revisiting Target‐Aware de novo Molecular Generation with TarPass: Between Rational Design and Texas Sharpshooter

Advanced Science, EarlyView.
TarPass provides a rigorous benchmark for target‐aware de novo molecular generation by jointly evaluating protein‐ligand interactions, molecular plausibility, and drug‐likeness on 18 well‐studied targets. Results show that current models often fail to consistently surpass random baseline in target‐specific enrichment, while post hoc multi‐tier virtual ...
Rui Qin, Zijie Chen, Yurong Li, Meijing Fang, Longji Shen, Yilong Su, Odin Zhang, Qinghan Wang, Qun Su, Jike Wang, Tingjun Hou, Yu Kang   +11 more
wiley   +1 more source

COVID-19 Prevention Behaviors and Mistrust Among Black and Latino Public Housing Residents in NYC. [PDF]

Health Educ Behav
Mautner Wizentier M, Williams D, Choi J, Goodman MS, Guilamo-Ramos V, Hagan H.   +5 more
europepmc   +1 more source

COVID-19 Stay-At-Home Orders and Secondhand Smoke in Public Housing. [PDF]

Am J Prev Med, 2023
Gehlert S, Rees VW, Choi K, Jackson PD, Sheehan BE, Grucza RA, Paulson AC, Plunk AD.   +7 more
europepmc   +1 more source

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

Advanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang, Chenyu Deng, Zhengrong Gao, Chen Chen, Huimin Zheng, Yue Yang, Yan Wei   +6 more
wiley   +1 more source

Predicting social network homophily on common chronic disease risk behaviors among public housing residents. [PDF]

BMC Public Health
Casey SM, Velez M, McDonough R, Garcia RI, Gondal N, Heaton B.   +5 more
europepmc   +1 more source

Implementation Activities in Smoke-Free Public Housing: The Massachusetts Experience. [PDF]

Int J Environ Res Public Health, 2022
Lee B, Fung V, Cheng D, Winickoff JP, Rigotti NA, Shah R, McGlave C, Goldberg S, Song G, Doane J, Kingsley M, Henley P, Ursprung S, Banthin C, Levy DE.   +14 more
europepmc   +1 more source

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

Le logement social en Algérie à la période coloniale (années 1920-1960)

ABE Journal
Thierry Guillopé
doaj   +1 more source

The silent burden of intestinal parasitic infections and associated risk factors in Malaysian public housing schemes. [PDF]

Sci Rep
AbuBakar N, Behnke JM, Tang VYP, Rafael A, Reezal NA, Sahimin N, Lim YAL, Mohd Zain SN.   +7 more
europepmc   +1 more source

Structural Model for Socially Sustainable Public Housing Decision-Making in Chile. [PDF]

Int J Environ Res Public Health, 2023
Sierra L, Lizana M, Pino C, Ilaya-Ayza A, Neculman B.   +4 more
europepmc   +1 more source