Results 61 to 70 of about 29,817,608 (260)

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Dociekliwi jako nowy ruch społeczny: aspekty polityczne realizacji prawa dostępu do informacji publicznej w Polsce

open access: yesPoliteja, 2019
The Inquisitives as a New Social Movement: Political Aspects of Exercising the Right for the Access to Information in Poland In this paper, the author analyzes the new social movement labeled „The Inquisitives”.
Marcin Wałdoch
doaj   +1 more source

Public Health Information Dissemination [PDF]

open access: yes
Our Mission: To strengthen public health science and improve public health decision making and practice to achieve positive health outcomes.Our Services: Clinicians, public health professionals, policymakers, communities, and individuals need timely ...

core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Availability of Cadastral Data

open access: yesKartografija i Geoinformacije, 2007
Data and information within the authority of the government are information of the public sector for which the competent institutions are responsible. These data are normally public property.
Miodrag Roić, Vlado Cetl, Mario Mađer
doaj  

Pelaksanaan Jaring Aspirasi Sebagai Komunikasi Publik Pemerintah Daerah Kabupaten Kulon Progo

open access: yesJurnal Nuansa Akademik, 2019
Jaring Aspirasi is a liaison between the people and the local government leaders of Kulonprogo Regency. With the face-to-face model with a regent every Thursday, it is hoped that public information will be absorbed immediately to solve problems as soon ...
Bawa Supratman   +4 more
doaj   +1 more source

The Social Value of Public Information with Costly Information Acquisition

open access: yes, 2008
In a beauty contest framework, public authorities decide the accuracy of public information evaluating how it affects individual actions and private information acquisition.
Colombo, Luca Vittorio Angelo   +1 more
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