Results 121 to 130 of about 13,505,893 (305)

Institutions and public interest: public communication processes as instituting strategy

open access: yes, 2017
This article considers the processes of public communication provided by the institutions, presenting a proposal for addressing the communication centered on the normative, factual and strategic perspectives. Therefore, it develops the concepts of institution, public interest, public communication, organizational communication and strategy, emphasizing
openaire   +2 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Comparative Survey on the Records of Fixed Assets of Companies and Public Institutions [PDF]

open access: yes
This paper deals by way of comparison with the theoretical and practical methods to record the output and input of tangible fixed assets (non-current assets) in and from the patrimony of companies, on the one side and of public institutions, on the other
Ecobici, Nicolae
core  

Author Correction: Adherence to public institutions that foster cooperation. [PDF]

open access: yesNat Commun, 2021
Radzvilavicius AL   +2 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Decentralization and Political Institutions [PDF]

open access: yes
Does fiscal decentralization lead to more efficient governance, better public goods, and higher economic growth? This paper tests hypotheses of the theoretical literature that results of decentralization depend on features of political institutions ...
Ruben Enikolopov, Ekaterina Zhuravskaya
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

MARKETS, MOTIVATIONS AND PUBLIC GOODS: EXPERIMENTAL INVESTIGATIONS ON THE IMPACT OF INSTITUTIONS [PDF]

open access: yes
There are many factors which can motivate people to contribute to public goods. These range from intrinsic motivations such as altruism, through social motivations such as concerns for fairness and approval, to extrinsic incentives which include ...
John Tisdell, Andres Reeson
core  

A concise guide to effective management of the public works equipment fleet [PDF]

open access: yes, 1996
CIVINS (Civilian Institutions) Thesis documentThe purpose of this report is to present in a concise form the principles and fundamentals of managing the public works equipment fleet, providing a basis from which to develop an effective fleet management ...
De Armas, Vicente.
core   +1 more source

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