Results 121 to 130 of about 3,671,729 (308)

ILR Impact Brief - The Privatization of Public Higher Education: Can We Afford It? [PDF]

open access: yes, 2006
[Excerpt] Public colleges and universities are in danger of losing their place as engines of social mobility and generators of knowledge. State appropriations to public colleges and universities, as a share of their overall budgets, have been shrinking ...
Ehrenberg, Ronald G.
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Government Policy for the Procurement of Food from Local Family Farming in Brazilian Public Institutions. [PDF]

open access: yesFoods, 2021
Soares P   +5 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

R&D Internationalization, R&D Collaboration and Public Knowledge Institutions in Small Economies Evidence from Finland and the Netherlands [PDF]

open access: yes
This paper investigates innovating firms’ determinants of R&D collaboration with domestic universities and public knowledge institutes in Finland and the Netherlands.
Cees van Beers   +2 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

CHALLENGES AND BENEFITS OF DIGITALISATION FOR PUBLIC INSTITUTIONS IN ROMANIA [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie
In today's rapidly evolving digital landscape, the need for public institutions to embrace digitalization has become increasingly evident. In Romania, as in many other countries, the digital transformation of public institutions holds great potential
STAICULESCU OANA
doaj  

Towards the estimation of the economic value of the outputs of Scottish higher education institutions : Next Steps Summary Report [PDF]

open access: yes, 2008
This paper represents a summary of the 'Next Steps Project' which piloted the practical application of a new methodological approach applying welfare economic principles to estimate the value of non-market outputs of higher education institutions.
Brooks, Richard   +2 more
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

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