MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Instituições de Suporte, Serviços e Desempenho: um Estudo em Aglomeração Turística de Santa Catarina [PDF]
RAC: Revista de Administração Contemporânea, 2013 The objective of this study was to evaluate clusters of tourism support institutions on the northern coast of the Brazilian state of Santa Catarina state.
Valmir Emil Hoffmann +1 more
doaj
Institutions and public interest: public communication processes as instituting strategy
, 2017 This article considers the processes of public communication provided by the institutions, presenting a proposal for addressing the communication centered on the normative, factual and strategic perspectives. Therefore, it develops the concepts of institution, public interest, public communication, organizational communication and strategy, emphasizing
openaire +2 more sources
Curriculum study of Public Works Management [PDF]
, 1999 CIVINS (Civilian Institutions) Thesis documentCIVINSU.S.
Ellwood, John M.
core
American Fund for Israel Institutions presents : Israel Philharmonic Orchestra, 1951
, 2023 A souvenir program for the Israel Philharmonic Orchestra's first tour in the United States, sponsored by the American Fund for Israel Institutions. The orchestra performed in Toledo, Ohio on January 28, 1951 at the Peristyle of the Toledo Museum of Art ...
American Fund for Israel Institutions
core
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Public health training in public institutions' speech-language-hearing programs in Northeastern Brazil: a curricular framework study. [PDF]
Codas, 2023 Silva EMD +6 more
europepmc +1 more source
Predicting strategic change of public research institutions under unstable negative growth [PDF]
The purpose of this paper is to forecast and analyse, by a demographic perspective, the organizational behaviour of public research labs. The research focuses on the biggest Italian public research body.
Mario Coccia
core
Situational awareness : helping the new Navy chaplain understand preaching in terms of local theology and context [PDF]
, 2002 CIVINS (Civilian Institutions) Thesis documentApproved for public release; distribution is unlimited.http://archive.org/details ...
McLaughlin, Patrick James
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source