Results 91 to 100 of about 843,610 (313)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
INCOMES AND EXPENSES DEFINE ELEMENTS OF THE BUDGETARY ACCOUNTING OF PUBLIC INSTITUTIONS ACCOUNTING [PDF]
The process of reforming accounting has been transposed to the level ofpublic institutions for nearly 3 years. It was an audacious attempt by Cutting out theheavy legacy of the past, limited to income earned and expenses paid.
Iuliana Cenar
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Development of eating behavior: the way from infancy to adolescence. Review of foreign studies
Клиническая и специальная психология, 2016 Studies examining development of eating behavior in different age groups are reviewed. Determinants of disordered eating attitudes from infancy to adolescent are particularly examined. Family environment and social context are general factors. Knowledge,
Durneva M.U.
doaj
Anomaly Detection Module for Network Traffic Monitoring in Public Institutions. [PDF]
Sensors (Basel), 2023 Wawrowski Ł +10 more
europepmc +1 more source
Cultivating Curriculum: How Investing in School Grounds, the Streetscape and Vacant Land as Urban Ecosystems can Address Food Security, the Community and Institutions of Public Education [PDF]
, 2019 CIVINS (Civilian Institutions) Thesis documentThe 2014 Agricultural Act (Economic Research Division) (aka: The Farm Bill) was an important limelight shone on the issue of access to healthy foods, food education and the correlation between an increasingly
McAllister, Karen Elizabeth
core
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Public Procurement of Innovation Diffusion: Exploring the Role of Institutions and Institutional Coordination [PDF]
The role of the public agency as a pacer of private sector innovation has been emphasised over the recent years, especially in the context of the EU.
Bakker, Elmer +2 more
core
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source