Results 81 to 90 of about 2,442,163 (295)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

We must overcome our atomization to beat back neoliberal fascism

open access: yesPraxis Educativa, 2020
The work focuses on education, social atomization and the terror of political authoritarianism and neoliberal fascism. Two different political tremors that shake the world these days are analyzed: on the one hand, the spread of resistance to the ...
Henry Giroux
doaj   +4 more sources

Endoscopic ultrasound-guided pancreatic pseudocyst drainage using a drill dilator

open access: yesEndoscopy International Open, 2023
Takeshi Okamoto   +2 more
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Public-interest services revisited [PDF]

open access: yesJournal of European Public Policy, 2002
The provision of utilities for all at an affordable price has long been regarded as a prerequisite for everyday life, generally guaranteed by the state. But in recent years, publicly owned utilities throughout Europe have come under increasing fire for their poor performance--their lack of productive efficiency, their failure to identify consumer ...
openaire   +4 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Public Interest Internship Panel

open access: yes
Thursday, November 21, 2024 | 12:45 PM | Eck Hall of Law, Room 3130 Join PILF\u27s E-Board in their discussion and Q&A of their summer internship experience, the application process, and anything public interest related in Eck 3130 at 12:45pm.
Public Interest Law Forum
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Extension of the Faustmann formula for tree economic calculations; illustrations in the case of beech forest in the North-East of France [PDF]

open access: yesتحقیقات جنگل و صنوبر ایران, 2007
The decision on the tree scale constitutes smallest and the most concrete scale of decision in forest management. All decisions concerning of the forest trees (cut, selection of species, etc.) are often found on the basis of the technical and economic ...
Sayyed Mahdi Heshmatol Vaezin   +1 more
doaj  

Public Interest Law Forum Welcome Meeting

open access: yes
Thursday, September 19, 2024 | 12:30 PM | Eck Hall of Law, Room 1140 Join the Public Interest Law Forum for our welcome meeting where we will introduce the E-board, elect 1L Reps and the Media Manager, and talk about public interest!
Public Interest Law Forum
core  

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