Results 61 to 70 of about 2,442,163 (295)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
, 2013 PIAC identifies public interest issues and, where possible and appropriate, works co-operatively with other organisations to advocate for individuals and groups affected.
Public Interest Advocacy Centre
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
La formulation contractuelle de l’intérêt général entre droits et intérêts particuliers
Astérion, 2017 By making the individual rights the anthropological premise of society, modernity subverted the essence of the common good which is now defined with regard to individual aspirations. The general interest can no longer be regarded as an end.
Florence Perrin
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
, 2020 This is a one-pager from the World Public Health Nutrition Association regarding reporting a conflict of interest; for instance, in schools: “promoting and providing ultra-processed foods and products while implementing "educational activities" in ...
World Public Health Nutrition Association
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, 2021 Presented by Swinburne's Social Innovation Research Institute and La Trobe University. Public interest technologies put people and society at the centre of our technological choices and strive to ensure that the benefits of technology are widely shared ...
A/Prof Sam Wilson +3 more
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Beyond the prison gates: the experiences of people recently released from prison into homelessness and housing crisis [PDF]
, 2013 This paper outlines the key findings and themes from a consultation project exploring the experiences and difficulties faced by people who have recently exited the prison system into situations of housing crisis or homelessness.
Public Interest Advocacy Centre
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