Results 141 to 150 of about 1,462,384 (296)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Copyright\u27s Public Reliance Interests [PDF]
Courts are increasingly invoking copyright law’s “scenes a faire” doctrine, which precludes infringement liability for copying typical or standard elements in a copyrighted work.
Kim, Bo S. L.
core
ON THE RELATIVITY OF THE LIMITS OF PUBLIC AND PRIVATE INTERESTS IN CRIMINAL PROCEEDINGS
The distinction between private and public interests and the search for a balance between them in the system of criminal procedure regulation are in one way or another connected with all other theoretical and practical problems of criminal proceedings ...
TARASOV Aleksandr Alekseyevich
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Good Neighbourliness and Fundamental Rights Based Interpretations of Public-Policy Clauses in EU Private International Law [PDF]
The minimum standard of good neighbourliness in private international law is provided by the general principle of comity, which applies to all relationship between states that acknowledge private international law. Within the EU, higher standards of good
Basheska, Elena +2 more
core
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Trade-offs in infrastructure investment decisions:between financial and public interests [PDF]
The economic crisis of 2007 has limited financial resources of governments for public works and service. For this reason, asset managers of transport infrastructure need to make priorities on their investments.
Hartmann, A.; id_orcid, Schraven, D.F.J.
core
The political economy of mandatory disclosure: a literature review
Reviewing the literature on mandatory corporate disclosure from a political economy perspective, we synthesize the classic justifications for disclosure regulations while emphasizing why voluntary disclosure often fails to achieve socially efficient ...
Hao Liang, Hanyu Zhang
doaj +1 more source
Genetic Testing between Private and Public Interests: Some Legal and Ethical Reflections. [PDF]
Sándor J.
europepmc +1 more source

