Results 151 to 160 of about 1,462,384 (296)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Disagreement and Consensus: The Need for Dynamic Updating in Public Deliberation [PDF]
, 2005 This analysis compares a consensus-oriented procedure, Princeton Future, with a more adversarial procedure, the public meetings of the Princeton, N.J. borough council, organized as public hearings.
Karpowitz, Christopher F. +1 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Graduate thesis advisors: a directory of research interests and expertise [PDF]
, 2002 Plan BA Research Interests and Expertise Directory for graduate students is essential in making a good and informed choice of a thesis advisor. This directory lists the participating University of Wisconsin-Stout faculty eligible for thesis advising ...
Kardell, Lisa
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
The fog of integration: Reassessing the role of economic interests in European integration [PDF]
, 2007 The main theories of European economic integration argue that private economic interests play an important role in the integration process. This role is a positive one, whereby economic interests provide the impetus and pressures for integration to move ...
Patrick Leblond, Leblond, Patrick.
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Shrouded histories: Outlaw and Lawmaker, Republican politics and Women's Interests [PDF]
, 2003 This essay reads the novel of expatriate colonial writer Rosa Praed, Outlaw and Lawmaker (1893), as an intervention in the public debate about the Irish question and the marriage question which were vigorously discussed in the late 1880s in Britain, the ...
Ferres, Kay
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source