Results 231 to 240 of about 23,082,987 (350)

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Developing an Antenatal Intervention to Improve Vaccine Uptake Using Parent, Patient and Public Involvement and Engagement in Northern Ireland. [PDF]

Health Expect
McCarron SA, Patterson L, Hart N.
europepmc   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Patient and public involvement in pragmatic trials with older adults: a multi-methods study of researchers' experiences. [PDF]

BMC Geriatr
Spinewine A, Evrard P, Nevins P, Adda T, Vanderhout S, Branje K, Hutton J, Smith M, Taljaard M, Nicholls SG.   +9 more
europepmc   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Public involvement Insight Report - Proposed clinical trial to understand how Tirzepatide affects bone health in people living with obesity

Public involvement insights about a proposed trial for GLP1 ...
Wadhwa, ruchi, Piggin, Maria, Behary, Preeshila   +2 more
core  

Equitable partnership: patient and public involvement and engagement and community engagement in mental health research in Pakistan. [PDF]

Res Involv Engagem
Hamid S, Jamal SF, Shah SMU, Azeemi IT, Khan AJ, Sheikh S, Ayub T, Fonseka N, Milner A, Azeemi MMUH, Khan MF, Khan S, Nauman AA, Sanauddin N, Farooq S, Canvin K.   +15 more
europepmc   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Integrating patient and public involvement to strengthen oncology research in sub-Saharan Africa. [PDF]

BMJ Oncol
Hughes JG, Marzouk S, Mahatara EV, Tamirisa K, Rahim F, Bulbeck H, Kapologwe NA.   +6 more
europepmc   +1 more source

Mapping the impact of patient and public involvement on health and social care research: a systematic review

Health Expectations, 2014
J. Brett, S. Staniszewska, C. Mockford, S. Herron-Marx, John Hughes, C. Tysall, R. Suleman   +6 more
semanticscholar   +1 more source