Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Post Quantum Public and Private Key Cryptography Optimized for IoT Security
The number of Internet of Things devices is growing exponentially with the introduction of 5G. They are incorporated into a wide spectrum of devices ranging from our mobile phones to healthcare tracking devices.
Ananya Komal Singh +8 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Lightweight finite field operators for public key cryptography on resource-constrained devices. [PDF]
Nowadays, computational power is being used in various activities of human life. New computing paradigms such as the Internet of Things, wireless sensor networks, ubiquitous computing, and ambient intelligence make use of computing power to improve the ...
Luis Rodríguez
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Distributed Public-Key Cryptography from Weak Secrets [PDF]
The original publication is available at www.springerlink.comInternational audienceWe introduce the notion of distributed password-based public-key cryptography, where a virtual high-entropy private key is implicitly defined as a concatenation of low ...
Michel Abdalla +7 more
core +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
EthVault: A Secure and Resource‐Conscious FPGA‐Based Ethereum Cold Wallet
Cryptocurrency blockchain networks safeguard digital assets using cryptographic keys, with wallets playing a critical role in generating, storing, and managing these keys.
Joel Poncha Lemayian +3 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Inverse matrices with applications in public-key cryptography
The applications of non-square binary matrices span many domains including mathematics, error-correction coding, machine learning, data storage, navigation signals, and cryptography.
Farshid Haidary Makoui +1 more
doaj +1 more source

