MPXV infection leads to persistent viral replication and severe local inflammation, while existing treatments cannot simultaneously remove viruses and repair injured tissue. This study constructs Polymer@mPDA@Gel hydrogel via a two‐step hierarchical assembly method: mPDA anchors photothermal polymers to form antiviral photothermal subunits, which are ...
Ming Zhang +7 more
wiley +1 more source
Anonymous and Efficient Chaotic Map-Based Authentication Protocol for Industrial Internet of Things. [PDF]
Zeng D +6 more
europepmc +1 more source
Mepce Restrains Ferroptosis in Prostate Cancer Through 7SK–P‐TEFb Pause Control
Genome‐wide CRISPR screening identifies MEPCE as a pause‐control regulator that restrains ferroptosis in prostate cancer. MEPCE loss releases P‐TEFb/CDK9 from 7SK snRNP control, enhances RNAPII Ser2 phosphorylation, and accelerates NRF2‐HMOX1‐driven labile iron accumulation and lipid peroxidation, revealing a transcriptional kinetic gate that lowers ...
Tongtong Zhang +9 more
wiley +1 more source
Understanding the problem of chronic kidney disease in the Republic of Kazakhstan: the study on prevalence and patients' health behaviors. [PDF]
Burkutov Y +3 more
europepmc +1 more source
A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu +17 more
wiley +1 more source
Secure near-lossless medical image compression and encryption with image-specific post-quantum key management and blockchain-based verification. [PDF]
Yadav B, Arakeri M.
europepmc +1 more source
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv +16 more
wiley +1 more source
Evaluation of measles outbreak response in Geze Gofa district, South Ethiopia region, using the 7-1-7 timeliness metrics. [PDF]
Fekadu L +6 more
europepmc +1 more source
Bio‐Based Polyurethanes for Sustainable and Multifunctional Applications
Bio‐based polyurethanes prepared from vegetable oils, lignin, and polysaccharides have attracted increasing interest as alternatives to fossil‐derived polyurethanes. This review summarizes recent progress in their chemistry, structural engineering, and advanced applications, highlighting the roles of feedstocks, chain‐segment design, dynamic covalent ...
Xin Li +6 more
wiley +1 more source
Long-Term Outcomes of Transcatheter Versus Surgical Aortic Valve Replacement Among Patients With Prior Mediastinal Radiation. [PDF]
Elbenawi H +15 more
europepmc +1 more source

