Results 31 to 40 of about 17,293,984 (225)

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Revision rates after primary hip and knee replacement in England between 2003 and 2006 [PDF]

, 2008
<b>Background</b>: Hip and knee replacement are some of the most frequently performed surgical procedures in the world. Resurfacing of the hip and unicondylar knee replacement are increasingly being used.
Boroff, Mick, Pickford, M., Borroff, Mick, Keith Tucker, Tucker, K., MacGregor, Alex J., on behalf of the Steering Committee of the National Joint Regist, Macgregor, AJ, Copley, LP, Lynn P Copley, Lewsey, J.D., Pickford, M, Copley Lynn P, Lewsey, Jim D., Tucker, K, Copley, Lynn P, Borroff, M, Lewsey, JD, Gregg, Paul, Gregg, P, Pickford Martin, van der Meulen, JH, Porter, Martyn, Sibanda, N, Lewsey Jim D, Copley, L.P., Mick Borroff, Paul Gregg, Porter, M, Copley, Lynn P., Porter Martyn, Martyn Porter, Jan H van der Meulen, Sibanda Nokuthaba, Gregg Paul, MacGregor, A.J., Alex J MacGregor, Borroff Mick, van der Meulen, J.H., Steering Committee of the National Joint Registry (NJR) for England and Wales, Sibanda, Nokuthaba, MacGregor, Alex J, Tucker Keith, Pickford, Martin, Tucker, Keith, Nokuthaba Sibanda, Sibanda, N., van der Meulen, Jan H, Steering Committee of the National Joint Registry (NJR) for Engl, MacGregor Alex J, Porter, M., Gregg, P., van der Meulen, Jan H., Borroff, M., Martin Pickford, van der Meulen Jan H, Lewsey, Jim D, Jim D Lewsey   +57 more
core   +2 more sources

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons, Nuria Guillen, Jordi Sarto, Neus Falgàs, Sergi Borrego‐Écija, Diana Esteller‐Gauxax, Magda Castellví, Adrià Tort‐Merino, Agnès Pérez‐Millan, Anna Antonell, Josep M. Augè Fradera, Gerard Piñol, Iolanda Riba, Anna Carnes‐Vendrell, Marta Cullell, Maria Teresa Osuna, Lorena Bajo, Teresa Romero, Eva Bonjoch, Joan Bello, Susana Fernández, Marta Balagué, Isabel Gómez‐Ruiz, Anuncia Boltes, Claustre Pont, Raquel Cuevas, Sara Carrillo, Laura Iglesias, Teresa Maria Casadevall Codina, Lorena Grau Guinea, Fernando Jose Espada, Raquel Sánchez‐Valle, Mircea Balasa, Albert Lladó   +33 more
wiley   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

Security Analysis and Performance Evaluation of Certificateless Proxy Re-Encryption for Blockchain Applications

IEEE Access
Certificateless Proxy Re-Encryption (CL-PRE) eliminates certificate management and private key exposure risks for blockchain data sharing, but existing schemes have critical security vulnerabilities and performance limitations.
S. Remya, Manu J. Pillai, Preethi Ann Jacob, Sruthi Suresh, S. Sharmila Deva Selvi   +4 more
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

The Digital Signature of Blum-Goldwasser Probobilistic Public Key Cryptosystem [PDF]

, 1999
The digital signature algorithm for Blum-Goldwasser probabilistic public key cryptosystem is proposed. In the proposed cryptosystem both encryption and digita1 signature can be done at the same time. The security of the proposed cryptosystem is not lower
ODAKA, Tomohiro, 小倉, 久和, OGURA, Hisakazu, WANG, Shangping, 西野, 順二, 小高, 知宏, 王, 尚平, NISHINO, Junji   +7 more
core  

Wavelet-based fragile watermarking scheme for image authentication [PDF]

, 2007
We propose a fragile watermarking scheme in the wavelet transform domain that is sensitive to all kinds of manipulations and has the ability to localize the tampered regions.
Si, Huayin, Li, Chang-Tsun
core   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source