Results 81 to 90 of about 9,320,919 (411)

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf   +10 more
wiley   +1 more source

Open Source Integrated Library Systems in Public Libraries [PDF]

open access: yes, 2013
One of the most fundamental decisions a library makes is choosing an integrated library system, or ILS. A public library can remove unwanted outside influence and save money by switching their ILS to free and open source software, or FOSS.
Brooke, Tony
core   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Partnering Public Library services with Public Schools

open access: yesWOW Stories, 2013
The Washington County Public Library worked with kindergarten teachers to implement lessons that would broaden the students' understandings of global cultural through global picturebooks and crafts, food, and music. This vignette discusses the books read,
Heather Dantzler , Jessica Ross
doaj  

Library Materials For Children [PDF]

open access: yes, 1977
Library materials for children cannot be considered alone, because the term library has long implied more than a collection of books. It is fitting that this topic follows papers discussing goals, facilities, staff, services, and children themselves ...
Carlson, Dudley B.   +1 more
core  

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

open access: yesMolecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa   +14 more
wiley   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

The value-semantic paradigm of the library science’ knowledge: choice of evolutionary suitable foundations

open access: yesБиблиосфера, 2019
The value-semantic paradigm of the library science’ knowledge undergoes constant changes understandable only in the context of its evolution. It is due to a number of factors, namely: transformation of the scientific knowledge system as a whole; changes ...
G. M. Vikhreva, O. P. Fedotova
doaj   +1 more source

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

open access: yesFEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source

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