Results 91 to 100 of about 433,816 (309)

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Quality of Public Open Spaces in Tirana

open access: yesEuropean Journal of Architecture and Urban Planning
With the fall of the communist regime and the start of land privatization, Tirana went through a period of rapid urban expansion that generated an unprecedented explosion of informal settlements and the loss of public/collective spaces. This transformation is reflected in urban form and spatial configuration/perception of the public spaces.
Jonila Prifti, Juljan Veleshnja
openaire   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

The Sustainability Coefficient of Urban Open Space Illumination Compliance as a Subjective Indicator of Environmental Comfort

open access: yesApplied Sciences
Smart lighting of public open spaces plays a crucial role in creating sustainable cities. Investing in optimal methods for improving the energy efficiency of urban lighting systems has become strategic for the economic, technological, and social ...
Melita Rozman Cafuta
doaj   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Multisensory Comfort in Public Open Spaces

open access: yesDIMENSI (Journal of Architecture and Built Environment)
This study investigates comfort in public open spaces in Bandung by linking measured environmental conditions with visitor perceptions collected through questionnaires. Logistic regression was applied to model the relationship between the two data sets. The model achieved good discriminatory power for predicting comfort, with Area Under the Curve (AUC)
Ni Putu Amanda Nitidara   +2 more
openaire   +1 more source

Empowering Adult Learning How AI Fuels Progress Across Disciplines and Professions

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article examines the evolving role of artificial intelligence (AI) as a transformative cognitive partner across educational and professional fields. It explores how AI shifts attention away from routine technical tasks and toward human‐centered skills such as critical thinking, ethical decision‐making, and professional judgment.
Rachel Wlodarsky
wiley   +1 more source

Multidimensional Spatial Vitality Automated Monitoring Method for Public Open Spaces Based on Computer Vision Technology: Case Study of Nanjing’s Daxing Palace Square

open access: yesISPRS International Journal of Geo-Information
Assessing the vitality of public open spaces is critical in urban planning and provides insights for optimizing residents’ lives. However, prior research has fragmented study scopes and lacks fine-grained behavioral data segmentation capabilities and ...
Xinyu Hu   +4 more
doaj   +1 more source

Elements that influence living quality in open urban space [PDF]

open access: yesUrbani Izziv, 2007
The number of people living in cities in Slovenia is increasing. There fore, the city spreads, urban space is created mostly by different buildings with minimum of open space, usually designed for parking spaces.
Petra Krajner
doaj  

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