Results 31 to 40 of about 34,497,009 (302)

ANALISIS KECUKUPAN RUANG TERBUKA HIJAU (RTH) KOTA BATAM

Jurnal Belantara, 2021
Batam City is an industrial city and has a total area of 1,570.35 km2 with a land area of 715 km2. Following the economic development and increasing population, the green open space in Batam City is decreasing.
Shirly Indriana Putri, Nurul Qomar, Yossi Oktorini   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Public Space and Security: Samsun/Batipark Sample

Proceedings of the International Conference of Contemporary Affairs in Architecture and Urbanism-ICCAUA
This study examines the perception of security in public spaces and the parameters that determine this perception in the context of open and green spaces.
Berna İzel GÜNGÖR, Tuğçe ŞANLI KATI   +1 more
doaj   +1 more source

Utilization of Public Open Space: Movement Pattern and Compromised Territory [PDF]

E3S Web of Conferences
Understanding open space management based on local culture is an important aspect in creating an inclusive quality of community life. Serang City Square is a public space that has high vitality in its utilization for the local community.
Ausi Shintaya, Puspitasari Popi
doaj   +1 more source

Watch This Space! Designing for Children's Play in Public Open Spaces [PDF]

Geography Compass, 2008
Abstract This article reviews one important aspect of children's environments in urban areas: play in public open spaces. The focus is on the provision of spaces for play for children aged between about 4–11 years old. The article argues that children's play is important for their development and for society as a whole and the article
openaire   +2 more sources

2020: A Year without Public Space

, 2021
After working from home for more than five hundred days, our daily lives and rituals have been severely changed by the COVID-19 pandemic. Moreover, social distancing and other measures have affected everyone’s access to public space and exposed a range ...
Harteveld, Maurice (author)
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Appropriation of public space

, 2020
Publicness is a crucial concept in urban design practice that provides a critical though constructive backdrop to approaches and strategies that go beyond simply designing ‘public space.’ Planning and building public spaces are among the objectives of ...
Haas, Tigran,, Tigran Haas, Karimnia, Elahe, Elahe Karimnia   +3 more
core   +1 more source