Results 51 to 60 of about 433,816 (309)

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Conceptual commentary of public spaces in Durban, South Africa

open access: yesTown and Regional Planning, 2018
Within the context of African cities that are considered to have poor economic prospects and are failing its inhabitants, this article explores and assesses the quality of Durban’s open public spaces through a phenomenological lens, by applying the ...
Magdalena Cloete, Salena Yusuf
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

SURVEI MINAT MASYARAKAT TERHADAP PEMANFAATAN RUANG TERBUKA PUBLIK SEBAGAI TEMPAT BEROLAHRAGA DI KOTA SALATIGA TAHUN 2013

open access: yesActive: journal of physical education, sport, health and recreation, 2015
This study aims to determine the Salatiga public interest in utilizing public open space as a place to work out in the 2013.The technique to obtain data that is by spreading the sample questionnaire respondents from each age category, the group of ...
Diego Satriawan
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Hybrid open public space of landscape elements and built structure [PDF]

open access: yesUrbani Izziv, 2008
The trend today in the cities in Europe and elsewhere is in combining landscape elements, built structure and different uses into a complex urban structure. Physical and program interweaving of landscape elements and built structure enables the consumers
Gordana Bence
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Park Politics

open access: yesSpool, 2018
In June 2018, professionals and scholars, from various fields dealing with public open spaces, put politics up for discussion. In the conference series x–LArch at the University of Natural Resources and Life Sciences, BOKU/Vienna, issues are raised that
Lilli Lička   +2 more
doaj   +2 more sources

Balance of Green Open Space to Support Green Settlement in Yogyakarta Urban Area

open access: yesJurnal Sains & Teknologi Lingkungan, 2017
The greatest problem relating to settlement growth in Yogyakarta urban area is the declining number of green open spaces. This study aimed to analyze the balance between the availability of and need for green open space development to promote the ...
Widodo Brontowiyono
doaj   +1 more source

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