Results 61 to 70 of about 433,816 (309)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Observation and behavioural maps. Methods of researching public open spaces in cities [PDF]

open access: yesUrbani Izziv, 2002
The paper presents some methods from a current research that investigates the effectiveness of public urban open space in meeting spatial dimensions and human needs.
Barbara Goličnik   +1 more
doaj  

Study on Relationship between Roles of Public Open Spaces and Pedestrians Inside Campus

open access: yesActa Technica Jaurinensis, 2020
Public open spaces in campuses are social places for students and staffs. Convenient accessibility both physical and visual is the main factor that attracts people to use these spaces.
Chompoonut Kongphunphin   +2 more
doaj   +1 more source

The Atmosphere in Open Public Spaces

open access: yes, 2018
Introduction: A space’s atmosphere is an important factor in how that space is experienced. In fact, festival visitors consider the atmosphere as the most important factor in how they experience a festival (Van Vliet 2012). Atmosphere is also what distinguishes physical shops from online web shops (Van Vliet, Moes & Schrandt 2015).
van Vliet, Harry   +3 more
openaire   +2 more sources

The Alignment of Public Open Space Elements with Visitor Motivation in the Musi Riverfront Public Open Space

open access: yesArchvisual: Jurnal Arsitektur dan Perencanaan
Public open spaces are considered successful when they are continuously visited and provide tangible benefits to their users. Individuals’ intentions to visit a place, including public open spaces, are driven by internal motivations, whereas the choice of a specific destination is influenced by the elements present within the space.
Almira Ulfa   +4 more
openaire   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Research on the open space ratios of residential plots in major Chinese cities meeting public centralized green space standards

open access: yesScientific Reports
The indicator of open space ratio has garnered significant international attention due to its ability to effectively balance equity and efficiency in urban development.
Bingjing Zhao   +4 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

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