Results 31 to 40 of about 1,544,518 (260)

Bridging healthcare gaps through specialized mobile healthcare services to improve healthcare access and outcomes in rural Hungary

Scientific Reports
Telemedicine offers promising solutions to healthcare challenges in underserved rural areas. This study evaluates a public insurance-based telemedicine system implemented in Hungary, where 12 Mobile Healthcare Service Centers (MHSCs) provided general and
Mark Virag, Rita Kovacs, Gergely Marovics, Luca Toth, Barbara Sandor, Peter Voros, Veronika Gyori–Dani, Ferenc Nagy, Daniel Eorsi, Janos Sandor, Istvan Kiss, Ferenc Vincze, Anita Palinkas, Abel Perjes, Szilard Rendeki, Peter Maroti   +15 more
doaj   +1 more source

The Evolution of Public Order and Public Policy in EU Law: Europeanisation of Essential State Functions and the Union’s Public Order

European Papers
(Series Information) European Papers - A Journal on Law and Integration, 2024 9(3), 1474-1485 | Article | (Table of Contents) I. Introduction. – II.
Stephen Coutts
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Differential use of various types of pessaries in isthmic-cervical insufficiency for prevention of preterm birth: A randomized prospective trial

Кубанский научный медицинский вестник
Background. Obstetric pessary comprises one of the methods for treatment of isthmic-cervical insufficiency. Despite the variety of pessaries produced, the common purpose of their use consists in preventing premature birth.
T. N. Zakharenkova, Yu. D. Kaplan, S. N. Zanko, T. N. Kovalevskaya   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Public order offences

Oñati Socio-Legal Series
As an area of law in the UK, public order offences are almost entirely useless on social media. This set of offences (ss. 4, 4A and 5 of the Public Order Act 1986) was aimed to address any behaviour or expressive activities, either oral or written ...
Iñigo Gordon Benito
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Analysis of key threats to European security and the Republic of Moldova

Науковий вісник Ужгородського національного університету. Серія Право, 2023
In humanitarian law, the terms public order or public security describe the general conditions that must exist for citizens to enjoy their rights and freedoms. States thus become responsible for the defense of public safety.
V. Ursu
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source