Results 91 to 100 of about 11,488,763 (293)
Lactate accumulation in glioblastoma drives lactylation of STING at lysine 370, a primate‐conserved residue. K370 lactylation weakens STING‐TBK1 binding, destabilizes STING, and disrupts ER‐to‐Golgi trafficking, blunting type I interferon signaling. LDHA inhibition reverses K370 lactylation and improves the antitumor efficacy of STING agonism combined ...
Yueyao Wu +11 more
wiley +1 more source
Integrating Environmental Sustainability into Public Procurement: Evidence from Ghanaian Local Government Entities [PDF]
Environmental sustainability is a growing concern for governments as they strive to promote responsible production and consumption within the public sector.
Amankwaa Asiedu
doaj +1 more source
PUBLIC PROCUREMENT AS TOOL OF ENVIRONMENTAL POLICY [PDF]
Correlating private and social interests represents a continuous challenge for environmental policy. Traditional implementation tools proved to be not enough for accomplishing the objectives required by the protection of natural systems.
Ildiko IOAN, Florina BRAN
core
Ex‐spRandom is a spatial transcriptomics platform that synergizes random‐primed chemistry with iterative hydrogel expansion. By physically decrowding the dense FFPE matrix, this scalable technology shatters the traditional resolution‐sensitivity barrier.
Shunji Zhang +7 more
wiley +1 more source
FINANCIAL CONTROL OF GOVERNMENT PROCUREMENT
The article deals with the peculiarities of state financial control in the public procurement system of Russia. In connection with the changes observed in the public procurement system, the issue of their state financial control is important.
A. Sokolova, O. Chokhatarova
doaj
A unified time‐series forecasting framework learns transferable battery capacity‐degradation patterns from 20 heterogeneous datasets spanning chemistries, formats, temperatures, and cycling conditions. A single model delivers competitive predictions on both known and previously unseen datasets, while physics‐guided representation learning improves ...
Joey Chan +8 more
wiley +1 more source
Public procurement in the Czech Republic: Focused on regional development and e-procurement
Relations between public procurement, regional development, and e-procurement are discussed in this chapter. First, main themes of the debate are reviewed.
Machů, Jiří +2 more
core +1 more source
Corruption risk factors: an analysis of public procurement in Nigeria [PDF]
Nigeria has consistently ranked 6th amongst oil-producing nations of the world but despite the enormous revenues from the sale of petroleum resources in the past five decades, the country has made little advance in terms of infrastructure, quality of ...
Ekwo, Grace
core
Proposed molecular mechanism: NSUN6 catalyzes m5C methylation on Snail mRNA to enhance its stability, leading to Snail upregulation and EMT promotion. The first‐in‐class inhibitor AL398 suppresses endometrial cancer metastasis by targeting the NSUN6‐m5C‐Snail. axis. ABSTRACT Endometrial cancer (EC) constitutes a leading gynecologic malignancy for which
Xiangzhuan Zhao +19 more
wiley +1 more source
Auction versus Negotiation in Public Procurement: Looking for Empirical Evidence [PDF]
The relative efficiency of auctions and negotiations is still a puzzle in the literature. While auctions are the prescribed procedures and the most used ones for public procurement, in the private sector, where buyers are free to choose their purchasing ...
Anne Yvrande-Billon +2 more
core

