Results 101 to 110 of about 11,488,763 (293)

Matrix Stiffness Orchestrates Mesenchymal Stem Cell Lineage Commitment Toward Osteogenesis and Adipogenesis Through the PIEZO1/SP1/STC2 Axis

Advanced Science, EarlyView.
Matrix stiffness directs mesenchymal stem cell lineage commitment through PIEZO1‐dependent activation of the SP1/STC2 pathway. Stiff matrices favor osteogenesis and suppress adipogenesis, whereas the loss of PIEZO1 function impairs early bone formation. STC2 retains lineage‐regulatory activity even when PIEZO1 is inactive.
Shuo Zhang, Siteng Li, Wenzhong Chen, Qingcheng Song, Haiyue Zhao, Peng Wang, Yiran Zhang, Wenquan Liang, Shaowei Zheng, Juan Wang, Wei Chen, Yanbin Zhu, Yingze Zhang   +12 more
wiley   +1 more source

Evaluating Corruption-Prone Public Procurement Stages for Blockchain Integration Using AHP Approach

Systems
Corruption in public procurement remains a challenge to good governance, especially in developing nations. Blockchain technology has been espoused as a new paradigm for achieving sustainable public procurement practices for effective service delivery and,
Gideon Adjorlolo, Zhiwei Tang, Gladys Wauk, Philip Adu Sarfo, Alhassan Baako Braimah, Richard Blankson Safo, Benedict N-yanyi   +6 more
doaj   +1 more source

Macroeconomic effects of cost savings in public procurement [PDF]

The paper analyses the macroeconomic gain from cost savings in public procurement in an extended version of QUEST III. Labour tax cuts in response to cost savings from cheaper procurement (0.5 pp mark-up decline per year over 10 years and 20% of ...
Lukas VOGEL
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Hyper‐Intense Tumor Peripheral Accumulation of Antibody‐Conjugated Iron Oxide Nanoparticles can Enable Breast Cancer Detection by Magnetic Particle Imaging

Advanced Science, EarlyView.
Tumor‐associated inflammation retains antibody‐targeted or non‐specific antibody conjugated nanoparticles within the tumor microenvironment. Magnetic Particle Imaging (MPI) enables non‐invasive detection and differentiation of tumors from other organs, owing to higher nanoparticle retention by inflammatory cells in the tumor periphery.
Preethi Korangath, Hayden Carlton, Theresa Wong, Sean Healy, Toby Sanders, Mason Song, Patrick W. Goodwill, Cordula Grüttner, Kathleen Gabrielson, Robert Ivkov   +9 more
wiley   +1 more source

Public procurement in the presence of capital taxation [PDF]

The paper considers governments' public procurement decision as a way of influencing industry structure. In a federation in which capital is mobile and capital taxation is harmonized, a home bias in public procurement can potentially be explained as an ...
Weichenrieder, Alfons J.
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DIXDC1 Promotes Lymphatic Metastasis and Resistance to Cuproptosis in Bladder Cancer Through Mediating DLAT

Advanced Science, EarlyView.
DIXDC1 drives bladder cancer progression by binding and stabilizing DLAT. This axis enhances NEK7 and CCNE2 mRNA stability to promote proliferation and lymphatic metastasis, while limiting copper‐induced DLAT oligomerization to reduce cuproptosis sensitivity, identifying DIXDC1 as a potential target linking metastasis with cuproptosis resistance ...
Hongqiong Li, Liang Cheng, Xiaole Lu, Haonan Dong, Shi Fu, Hongjin Shi, Mingsheng Liu, Chenwei Yang, Yuhang Huang, Zehua Chen, Yawei Zhang, Kaiwen Jie, Xiaoyue Zhang, Xiang Kui, Xinni Ye, Siting Chen, Xu Chen, Haifeng Wang   +17 more
wiley   +1 more source

About the concept and content of legal regulation of public procurement

Halyk̦aralyk̦ k̦atynastar ža̋ne halyk̦aralyk̦ k̦u̇k̦yk̦ seriâsì, 2018
The article discloses the concept of public procurement, as well as the general characteristics of the fundamental international legal instruments in the field of regulation of public procurement.
A. Begzhan, Zh. Umbetbayeva
doaj  

Keeping Pace or Falling Behind? The Depth of Latin American Trade Agreements

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT This article examines whether Latin American countries are keeping pace with global trends in trade agreement depth or falling behind. Using 681 agreements (1970–2019), we develop the Depth Index of Trade Agreements (DITA) to weight provisions endogenously through factor analysis based on co‐occurrence patterns.
Raphael Gomes da Silva, Fernanda Aparecida Silva, Lia Nogueira   +2 more
wiley   +1 more source

Assessing Photovoltaic Recycling Capacities and Policy Gaps in the European Union

Advanced Energy and Sustainability Research, EarlyView.
This study maps photovoltaic recycling capacity in the EU and key global regions, highlighting gaps between growing waste volumes and available infrastructure. It combines survey insights and policy analysis to identify recycling bottlenecks and offers recommendations to boost circularity in the solar sector.
Nieves Espinosa, Silvia Bobba, Cynthia E. L. Latunussa, Enrica Leccisi   +3 more
wiley   +1 more source

What factors influence the uptake of GPP (Green Public Procurement) practices? New evidence from an Italian survey [PDF]

Green Public Procurement (GPP) is becoming a cornerstone of environmental policies both at European Union and Member State level. Drawing upon a database of public authorities located in three Italian Regions, this paper assesses the determinants and ...
Marco Frey, Francesco Testa, Fabio Iraldo, Tiberio Daddi   +3 more
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