Results 41 to 50 of about 13,874,377 (264)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Implementation fidelity to the World Health Organization package of essential non-communicable disease interventions (PEN) during scale-up in Nepal’s primary healthcare system: a mixed methods study

open access: yesImplementation Science Communications
Background The World Health Organization package of essential non-communicable disease interventions (PEN) comprises evidence-based interventions for primary healthcare systems in low- and middle-income countries (LMICs). Implementation fidelity, defined
Felix Teufel   +20 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Public finance in adjustment programs [PDF]

open access: yes
This paper reviews the experience with public finance issues under adjustment programs. This experience shows that fiscal changes are often triggered by budget and balance of payment crises.
Khalilzadeh-Shirazi, Javad   +1 more
core  

Factors associated with parental intentions to vaccinate 0-4-year-old children against COVID-19 in Canada: a cross-sectional study using the Childhood COVID-19 Immunization Coverage Survey (CCICS)

open access: yesBMC Public Health
Background The objective of this study was to determine the factors associated with low or no parental intention to vaccinate children of 0-4-years in Canada with a COVID-19 vaccine through the 2022 Childhood COVID-19 Immunization Coverage Survey (CCICS).
Israa Zareef   +7 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Mississippi River Network: Headwaters to Gulf

open access: yesOpen Rivers, 2017
How can dozens or even hundreds of organizations working on the Mississippi River be harnessed into a powerful body that has demonstrable influence in our nation’s capital, in capitals of states along the river, and in other places where the health of ...
Kelly McGinnis
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Public choices between lifesaving programs : how important are lives saved? [PDF]

open access: yes
In developing and industrial countries alike, there is concern that health and safety policy may respond to irrational fears - to the"disaster of the month"- rather than address more fundamental problems.
Cropper, Maureen L., Subramanian, Uma
core  

Which program for whom? Evidence on the comparative effectiveness of public sponsored training programs in Germany [PDF]

open access: yes, 2007
We use a new and exceptionally rich administrative data set for Germany to evaluate the employment effects of a variety of public sponsored training programs in the early 2000s.
Fitzenberger, B.   +3 more
core  

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